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The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.
Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, Laskey RA, Caldas C, Brenton JD. Ahmed AA, et al. Among authors: brenton jd. Cancer Cell. 2007 Dec;12(6):514-27. doi: 10.1016/j.ccr.2007.11.014. Cancer Cell. 2007. PMID: 18068629 Free PMC article.
Chromosomal instability determines taxane response.
Swanton C, Nicke B, Schuett M, Eklund AC, Ng C, Li Q, Hardcastle T, Lee A, Roy R, East P, Kschischo M, Endesfelder D, Wylie P, Kim SN, Chen JG, Howell M, Ried T, Habermann JK, Auer G, Brenton JD, Szallasi Z, Downward J. Swanton C, et al. Among authors: brenton jd. Proc Natl Acad Sci U S A. 2009 May 26;106(21):8671-6. doi: 10.1073/pnas.0811835106. Epub 2009 May 19. Proc Natl Acad Sci U S A. 2009. PMID: 19458043 Free PMC article.
Two novel determinants of etoposide resistance in small cell lung cancer.
Lawson MH, Cummings NM, Rassl DM, Russell R, Brenton JD, Rintoul RC, Murphy G. Lawson MH, et al. Among authors: brenton jd. Cancer Res. 2011 Jul 15;71(14):4877-87. doi: 10.1158/0008-5472.CAN-11-0080. Epub 2011 Jun 3. Cancer Res. 2011. PMID: 21642373 Free PMC article.
Computational pathology of pre-treatment biopsies identifies lymphocyte density as a predictor of response to neoadjuvant chemotherapy in breast cancer.
Ali HR, Dariush A, Provenzano E, Bardwell H, Abraham JE, Iddawela M, Vallier AL, Hiller L, Dunn JA, Bowden SJ, Hickish T, McAdam K, Houston S, Irwin MJ, Pharoah PD, Brenton JD, Walton NA, Earl HM, Caldas C. Ali HR, et al. Among authors: brenton jd. Breast Cancer Res. 2016 Feb 16;18(1):21. doi: 10.1186/s13058-016-0682-8. Breast Cancer Res. 2016. PMID: 26882907 Free PMC article. Clinical Trial.
European experts consensus: BRCA/homologous recombination deficiency testing in first-line ovarian cancer.
Vergote I, González-Martín A, Ray-Coquard I, Harter P, Colombo N, Pujol P, Lorusso D, Mirza MR, Brasiuniene B, Madry R, Brenton JD, Ausems MGEM, Büttner R, Lambrechts D; European experts’ consensus group. Vergote I, et al. Among authors: brenton jd. Ann Oncol. 2022 Mar;33(3):276-287. doi: 10.1016/j.annonc.2021.11.013. Epub 2021 Dec 1. Ann Oncol. 2022. PMID: 34861371 Free article. Review.
204 results