Carr R - Search Results

1

Phase 0 trials: an industry perspective.

Eliopoulos H, Giranda V, Carr R, Tiehen R, Leahy T, Gordon G. Eliopoulos H, et al. Among authors: carr r. Clin Cancer Res. 2008 Jun 15;14(12):3683-8. doi: 10.1158/1078-0432.CCR-07-4586. Clin Cancer Res. 2008. PMID: 18559583

2

Phase I dose-escalation study of the safety and pharmacokinetics of atrasentan: an endothelin receptor antagonist for refractory prostate cancer.

Zonnenberg BA, Groenewegen G, Janus TJ, Leahy TW, Humerickhouse RA, Isaacson JD, Carr RA, Voest E. Zonnenberg BA, et al. Clin Cancer Res. 2003 Aug 1;9(8):2965-72. Clin Cancer Res. 2003. PMID: 12912943 Clinical Trial.

3

Randomized, phase II study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced soft tissue sarcoma.

Baker LH, Rowinsky EK, Mendelson D, Humerickhouse RA, Knight RA, Qian J, Carr RA, Gordon GB, Demetri GD. Baker LH, et al. J Clin Oncol. 2008 Dec 1;26(34):5583-8. doi: 10.1200/JCO.2008.17.4706. Epub 2008 Nov 3. J Clin Oncol. 2008. PMID: 18981463 Clinical Trial.

4

Dose-ranging study of the safety and pharmacokinetics of atrasentan in patients with refractory malignancies.

Ryan CW, Vogelzang NJ, Vokes EE, Kindler HL, Undevia SD, Humerickhouse R, André AK, Wang Q, Carr RA, Ratain MJ. Ryan CW, et al. Among authors: carr ra. Clin Cancer Res. 2004 Jul 1;10(13):4406-11. doi: 10.1158/1078-0432.CCR-04-0083. Clin Cancer Res. 2004. PMID: 15240529 Clinical Trial.

5

Atrasentan, an endothelin-receptor antagonist for refractory adenocarcinomas: safety and pharmacokinetics.

Carducci MA, Nelson JB, Bowling MK, Rogers T, Eisenberger MA, Sinibaldi V, Donehower R, Leahy TL, Carr RA, Isaacson JD, Janus TJ, Andre A, Hosmane BS, Padley RJ. Carducci MA, et al. Among authors: carr ra. J Clin Oncol. 2002 Apr 15;20(8):2171-80. doi: 10.1200/JCO.2002.08.028. J Clin Oncol. 2002. PMID: 11956279 Clinical Trial.

6

Preclinical discovery of candidate genes to guide pharmacogenetics during phase I development: the example of the novel anticancer agent ABT-751.

Innocenti F, Ramírez J, Obel J, Xiong J, Mirkov S, Chiu YL, Katz DA, Carr RA, Zhang W, Das S, Adjei A, Moyer AM, Chen PX, Krivoshik A, Medina D, Gordon GB, Ratain MJ, Sahelijo L, Weinshilboum RM, Fleming GF, Bhathena A. Innocenti F, et al. Pharmacogenet Genomics. 2013 Jul;23(7):374-81. doi: 10.1097/FPC.0b013e3283623e81. Pharmacogenet Genomics. 2013. PMID: 23670235 Free PMC article. Clinical Trial.

7

A phase 1 trial of 2 dose schedules of ABT-510, an antiangiogenic, thrombospondin-1-mimetic peptide, in patients with advanced cancer.

Gordon MS, Mendelson D, Carr R, Knight RA, Humerickhouse RA, Iannone M, Stopeck AT. Gordon MS, et al. Among authors: carr r. Cancer. 2008 Dec 15;113(12):3420-9. doi: 10.1002/cncr.23953. Cancer. 2008. PMID: 18932258 Free article. Clinical Trial.

8

The effect of hepatic insufficiency on the safety and pharmacokinetics of paricalcitol (Zemplar).

Carr RA, André AK, Chen P, Grabowski BA, Chang MS, Locke CS, Williams LA, Chojkier M. Carr RA, et al. Nephron Clin Pract. 2006;103(3):c100-5. doi: 10.1159/000092018. Epub 2006 Mar 13. Nephron Clin Pract. 2006. PMID: 16534233

9

Dual effects of rifampin on the pharmacokinetics of atrasentan.

Xiong H, Carr RA, Locke CS, Katz DA, Achari R, Doan TT, Wang P, Jankowski JR, Sleep DJ. Xiong H, et al. Among authors: carr ra. J Clin Pharmacol. 2007 Apr;47(4):423-9. doi: 10.1177/0091270007299928. J Clin Pharmacol. 2007. PMID: 17389551 Clinical Trial.

10

Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.

Katz DA, Carr R, Grimm DR, Xiong H, Holley-Shanks R, Mueller T, Leake B, Wang Q, Han L, Wang PG, Edeki T, Sahelijo L, Doan T, Allen A, Spear BB, Kim RB. Katz DA, et al. Among authors: carr r. Clin Pharmacol Ther. 2006 Mar;79(3):186-96. doi: 10.1016/j.clpt.2005.11.003. Epub 2006 Feb 17. Clin Pharmacol Ther. 2006. PMID: 16513443

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