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Early bactericidal activity and pharmacokinetics of the diarylquinoline TMC207 in treatment of pulmonary tuberculosis.
Rustomjee R, Diacon AH, Allen J, Venter A, Reddy C, Patientia RF, Mthiyane TC, De Marez T, van Heeswijk R, Kerstens R, Koul A, De Beule K, Donald PR, McNeeley DF. Rustomjee R, et al. Among authors: koul a. Antimicrob Agents Chemother. 2008 Aug;52(8):2831-5. doi: 10.1128/AAC.01204-07. Epub 2008 May 27. Antimicrob Agents Chemother. 2008. PMID: 18505852 Free PMC article. Clinical Trial.
Bactericidal mode of action of bedaquiline.
Hards K, Robson JR, Berney M, Shaw L, Bald D, Koul A, Andries K, Cook GM. Hards K, et al. Among authors: koul a. J Antimicrob Chemother. 2015 Jul;70(7):2028-37. doi: 10.1093/jac/dkv054. Epub 2015 Mar 8. J Antimicrob Chemother. 2015. PMID: 25754998
Novel antibiotics targeting respiratory ATP synthesis in Gram-positive pathogenic bacteria.
Balemans W, Vranckx L, Lounis N, Pop O, Guillemont J, Vergauwen K, Mol S, Gilissen R, Motte M, Lançois D, De Bolle M, Bonroy K, Lill H, Andries K, Bald D, Koul A. Balemans W, et al. Among authors: koul a. Antimicrob Agents Chemother. 2012 Aug;56(8):4131-9. doi: 10.1128/AAC.00273-12. Epub 2012 May 21. Antimicrob Agents Chemother. 2012. PMID: 22615276 Free PMC article.
Acquired resistance of Mycobacterium tuberculosis to bedaquiline.
Andries K, Villellas C, Coeck N, Thys K, Gevers T, Vranckx L, Lounis N, de Jong BC, Koul A. Andries K, et al. Among authors: koul a. PLoS One. 2014 Jul 10;9(7):e102135. doi: 10.1371/journal.pone.0102135. eCollection 2014. PLoS One. 2014. PMID: 25010492 Free PMC article.
315 results