Nijman IJ - Search Results

1

Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line.

Feitsma H, de Bruijn E, van de Belt J, Nijman IJ, Cuppen E. Feitsma H, et al. Among authors: nijman ij. Mutagenesis. 2008 Jul;23(4):325-9. doi: 10.1093/mutage/gen019. Epub 2008 May 9. Mutagenesis. 2008. PMID: 18469325

2

Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.

Feitsma H, Kuiper RV, Korving J, Nijman IJ, Cuppen E. Feitsma H, et al. Among authors: nijman ij. Cancer Res. 2008 Jul 1;68(13):5059-66. doi: 10.1158/0008-5472.CAN-08-0019. Cancer Res. 2008. PMID: 18593904

3

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel R, Toonen PW, Verheul M, van Roekel HS, Nijman IJ, Guryev V, Cuppen E. van Boxtel R, et al. Among authors: nijman ij. BMC Genomics. 2008 Oct 7;9:460. doi: 10.1186/1471-2164-9-460. BMC Genomics. 2008. PMID: 18840264 Free PMC article.

4

Efficient target-selected mutagenesis in Caenorhabditis elegans: toward a knockout for every gene.

Cuppen E, Gort E, Hazendonk E, Mudde J, van de Belt J, Nijman IJ, Guryev V, Plasterk RH. Cuppen E, et al. Among authors: nijman ij. Genome Res. 2007 May;17(5):649-58. doi: 10.1101/gr.6080607. Epub 2007 Apr 6. Genome Res. 2007. PMID: 17416746 Free PMC article.

5

Accurate SNP and mutation detection by targeted custom microarray-based genomic enrichment of short-fragment sequencing libraries.

Mokry M, Feitsma H, Nijman IJ, de Bruijn E, van der Zaag PJ, Guryev V, Cuppen E. Mokry M, et al. Among authors: nijman ij. Nucleic Acids Res. 2010 Jun;38(10):e116. doi: 10.1093/nar/gkq072. Epub 2010 Feb 17. Nucleic Acids Res. 2010. PMID: 20164091 Free PMC article.

6

Mutation discovery by targeted genomic enrichment of multiplexed barcoded samples.

Nijman IJ, Mokry M, van Boxtel R, Toonen P, de Bruijn E, Cuppen E. Nijman IJ, et al. Nat Methods. 2010 Nov;7(11):913-5. doi: 10.1038/nmeth.1516. Epub 2010 Oct 17. Nat Methods. 2010. PMID: 20953175

7

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer.

Kloosterman WP, Hoogstraat M, Paling O, Tavakoli-Yaraki M, Renkens I, Vermaat JS, van Roosmalen MJ, van Lieshout S, Nijman IJ, Roessingh W, van 't Slot R, van de Belt J, Guryev V, Koudijs M, Voest E, Cuppen E. Kloosterman WP, et al. Among authors: nijman ij. Genome Biol. 2011 Oct 19;12(10):R103. doi: 10.1186/gb-2011-12-10-r103. Genome Biol. 2011. PMID: 22014273 Free PMC article.

8

Systematic generation of in vivo G protein-coupled receptor mutants in the rat.

van Boxtel R, Vroling B, Toonen P, Nijman IJ, van Roekel H, Verheul M, Baakman C, Guryev V, Vriend G, Cuppen E. van Boxtel R, et al. Among authors: nijman ij. Pharmacogenomics J. 2011 Oct;11(5):326-36. doi: 10.1038/tpj.2010.44. Epub 2010 Jun 8. Pharmacogenomics J. 2011. PMID: 20531371 Free PMC article.

9

Multiplexed array-based and in-solution genomic enrichment for flexible and cost-effective targeted next-generation sequencing.

Harakalova M, Mokry M, Hrdlickova B, Renkens I, Duran K, van Roekel H, Lansu N, van Roosmalen M, de Bruijn E, Nijman IJ, Kloosterman WP, Cuppen E. Harakalova M, et al. Among authors: nijman ij. Nat Protoc. 2011 Nov 3;6(12):1870-86. doi: 10.1038/nprot.2011.396. Nat Protoc. 2011. PMID: 22051800

10

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.

Hatzis P, van der Flier LG, van Driel MA, Guryev V, Nielsen F, Denissov S, Nijman IJ, Koster J, Santo EE, Welboren W, Versteeg R, Cuppen E, van de Wetering M, Clevers H, Stunnenberg HG. Hatzis P, et al. Among authors: nijman ij. Mol Cell Biol. 2008 Apr;28(8):2732-44. doi: 10.1128/MCB.02175-07. Epub 2008 Feb 11. Mol Cell Biol. 2008. PMID: 18268006 Free PMC article.

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