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Cardiogenic small molecules that enhance myocardial repair by stem cells.
Sadek H, Hannack B, Choe E, Wang J, Latif S, Garry MG, Garry DJ, Longgood J, Frantz DE, Olson EN, Hsieh J, Schneider JW. Sadek H, et al. Among authors: frantz de. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6063-8. doi: 10.1073/pnas.0711507105. Epub 2008 Apr 17. Proc Natl Acad Sci U S A. 2008. PMID: 18420817 Free PMC article.
Small-molecule activation of neuronal cell fate.
Schneider JW, Gao Z, Li S, Farooqi M, Tang TS, Bezprozvanny I, Frantz DE, Hsieh J. Schneider JW, et al. Among authors: frantz de. Nat Chem Biol. 2008 Jul;4(7):408-10. doi: 10.1038/nchembio.95. Epub 2008 Jun 15. Nat Chem Biol. 2008. PMID: 18552832
Allosteric inhibition of hypoxia inducible factor-2 with small molecules.
Scheuermann TH, Li Q, Ma HW, Key J, Zhang L, Chen R, Garcia JA, Naidoo J, Longgood J, Frantz DE, Tambar UK, Gardner KH, Bruick RK. Scheuermann TH, et al. Among authors: frantz de. Nat Chem Biol. 2013 Apr;9(4):271-6. doi: 10.1038/nchembio.1185. Epub 2013 Feb 24. Nat Chem Biol. 2013. PMID: 23434853 Free PMC article.
Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model.
Zang QS, Sadek H, Maass DL, Martinez B, Ma L, Kilgore JA, Williams NS, Frantz DE, Wigginton JG, Nwariaku FE, Wolf SE, Minei JP. Zang QS, et al. Among authors: frantz de. Am J Physiol Heart Circ Physiol. 2012 May 1;302(9):H1847-59. doi: 10.1152/ajpheart.00203.2011. Epub 2012 Mar 9. Am J Physiol Heart Circ Physiol. 2012. PMID: 22408027 Free article.
Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.
Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK. Rogers JL, et al. Among authors: frantz de. J Med Chem. 2013 Feb 28;56(4):1739-47. doi: 10.1021/jm301847z. Epub 2013 Feb 18. J Med Chem. 2013. PMID: 23363003 Free PMC article.
51 results