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Variants for HDL-C, LDL-C, and triglycerides identified from admixture mapping and fine-mapping analysis in African American families.
Shetty PB, Tang H, Feng T, Tayo B, Morrison AC, Kardia SL, Hanis CL, Arnett DK, Hunt SC, Boerwinkle E; Candidate Gene Association Resource (CARe) Consortium; Rao DC, Cooper RS, Risch N, Zhu X. Shetty PB, et al. Among authors: risch n. Circ Cardiovasc Genet. 2015 Feb;8(1):106-13. doi: 10.1161/CIRCGENETICS.114.000481. Epub 2014 Dec 31. Circ Cardiovasc Genet. 2015. PMID: 25552592 Free PMC article.
Admixture mapping for hypertension loci with genome-scan markers.
Zhu X, Luke A, Cooper RS, Quertermous T, Hanis C, Mosley T, Gu CC, Tang H, Rao DC, Risch N, Weder A. Zhu X, et al. Among authors: risch n. Nat Genet. 2005 Feb;37(2):177-81. doi: 10.1038/ng1510. Epub 2005 Jan 23. Nat Genet. 2005. PMID: 15665825
Variants in CXADR and F2RL1 are associated with blood pressure and obesity in African-Americans in regions identified through admixture mapping.
Shetty PB, Tang H, Tayo BO, Morrison AC, Hanis CL, Rao DC, Young JH, Fox ER, Boerwinkle E, Cooper RS, Risch NJ, Zhu X; Candidate Gene Association Resource (CARe) Consortium. Shetty PB, et al. J Hypertens. 2012 Oct;30(10):1970-6. doi: 10.1097/HJH.0b013e3283578c80. J Hypertens. 2012. PMID: 22914544 Free PMC article.
Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations.
Franceschini N, Fox E, Zhang Z, Edwards TL, Nalls MA, Sung YJ, Tayo BO, Sun YV, Gottesman O, Adeyemo A, Johnson AD, Young JH, Rice K, Duan Q, Chen F, Li Y, Tang H, Fornage M, Keene KL, Andrews JS, Smith JA, Faul JD, Guangfa Z, Guo W, Liu Y, Murray SS, Musani SK, Srinivasan S, Velez Edwards DR, Wang H, Becker LC, Bovet P, Bochud M, Broeckel U, Burnier M, Carty C, Chasman DI, Ehret G, Chen WM, Chen G, Chen W, Ding J, Dreisbach AW, Evans MK, Guo X, Garcia ME, Jensen R, Keller MF, Lettre G, Lotay V, Martin LW, Moore JH, Morrison AC, Mosley TH, Ogunniyi A, Palmas W, Papanicolaou G, Penman A, Polak JF, Ridker PM, Salako B, Singleton AB, Shriner D, Taylor KD, Vasan R, Wiggins K, Williams SM, Yanek LR, Zhao W, Zonderman AB, Becker DM, Berenson G, Boerwinkle E, Bottinger E, Cushman M, Eaton C, Nyberg F, Heiss G, Hirschhron JN, Howard VJ, Karczewsk KJ, Lanktree MB, Liu K, Liu Y, Loos R, Margolis K, Snyder M; Asian Genetic Epidemiology Network Consortium; Psaty BM, Schork NJ, Weir DR, Rotimi CN, Sale MM, Harris T, Kardia SL, Hunt SC, Arnett D, Redline S, Cooper RS, Risch NJ, Rao DC, Rotter JI, Chakravarti A, Reiner AP, Levy D, Keating BJ, Zhu X. Franceschini N, et al. Among authors: risch nj. Am J Hum Genet. 2013 Sep 5;93(3):545-54. doi: 10.1016/j.ajhg.2013.07.010. Epub 2013 Aug 22. Am J Hum Genet. 2013. PMID: 23972371 Free PMC article.
The association of the vanin-1 N131S variant with blood pressure is mediated by endoplasmic reticulum-associated degradation and loss of function.
Wang YJ, Tayo BO, Bandyopadhyay A, Wang H, Feng T, Franceschini N, Tang H, Gao J, Sung YJ; COGENT BP consortium; Elston RC, Williams SM, Cooper RS, Mu TW, Zhu X. Wang YJ, et al. PLoS Genet. 2014 Sep 18;10(9):e1004641. doi: 10.1371/journal.pgen.1004641. eCollection 2014 Sep. PLoS Genet. 2014. PMID: 25233454 Free PMC article.
402 results