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Inv(11)(q21q23) fuses MLL to the Notch co-activator mastermind-like 2 in secondary T-cell acute lymphoblastic leukemia.
Metzler M, Staege MS, Harder L, Mendelova D, Zuna J, Fronkova E, Meyer C, Flohr T, Bednarova D, Harbott J, Langer T, Gesk S, Trka J, Siebert R, Dingermann T, Marschalek R, Niemeyer C, Rascher W. Metzler M, et al. Among authors: staege ms. Leukemia. 2008 Sep;22(9):1807-11. doi: 10.1038/leu.2008.50. Epub 2008 Mar 13. Leukemia. 2008. PMID: 18337764 No abstract available.
MondoA is highly overexpressed in acute lymphoblastic leukemia cells and modulates their metabolism, differentiation and survival.
Wernicke CM, Richter GH, Beinvogl BC, Plehm S, Schlitter AM, Bandapalli OR, Prazeres da Costa O, Hattenhorst UE, Volkmer I, Staege MS, Esposito I, Burdach S, Grunewald TG. Wernicke CM, et al. Among authors: staege ms. Leuk Res. 2012 Sep;36(9):1185-92. doi: 10.1016/j.leukres.2012.05.009. Epub 2012 Jun 29. Leuk Res. 2012. PMID: 22748921
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.
Richter GH, Plehm S, Fasan A, Rössler S, Unland R, Bennani-Baiti IM, Hotfilder M, Löwel D, von Luettichau I, Mossbrugger I, Quintanilla-Martinez L, Kovar H, Staege MS, Müller-Tidow C, Burdach S. Richter GH, et al. Among authors: staege ms. Proc Natl Acad Sci U S A. 2009 Mar 31;106(13):5324-9. doi: 10.1073/pnas.0810759106. Epub 2009 Mar 16. Proc Natl Acad Sci U S A. 2009. PMID: 19289832 Free PMC article.
110 results