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Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models.
Spoerke JM, O'Brien C, Huw L, Koeppen H, Fridlyand J, Brachmann RK, Haverty PM, Pandita A, Mohan S, Sampath D, Friedman LS, Ross L, Hampton GM, Amler LC, Shames DS, Lackner MR. Spoerke JM, et al. Among authors: fridlyand j. Clin Cancer Res. 2012 Dec 15;18(24):6771-83. doi: 10.1158/1078-0432.CCR-12-2347. Epub 2012 Nov 7. Clin Cancer Res. 2012. PMID: 23136191
Breast tumor copy number aberration phenotypes and genomic instability.
Fridlyand J, Snijders AM, Ylstra B, Li H, Olshen A, Segraves R, Dairkee S, Tokuyasu T, Ljung BM, Jain AN, McLennan J, Ziegler J, Chin K, Devries S, Feiler H, Gray JW, Waldman F, Pinkel D, Albertson DG. Fridlyand J, et al. BMC Cancer. 2006 Apr 18;6:96. doi: 10.1186/1471-2407-6-96. BMC Cancer. 2006. PMID: 16620391 Free PMC article.
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies.
Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, Lapuk A, Neve RM, Qian Z, Ryder T, Chen F, Feiler H, Tokuyasu T, Kingsley C, Dairkee S, Meng Z, Chew K, Pinkel D, Jain A, Ljung BM, Esserman L, Albertson DG, Waldman FM, Gray JW. Chin K, et al. Among authors: fridlyand j. Cancer Cell. 2006 Dec;10(6):529-41. doi: 10.1016/j.ccr.2006.10.009. Cancer Cell. 2006. PMID: 17157792 Free article.
FBXW7 and DNA copy number instability.
Byrd KN, Huey B, Roydasgupta R, Fridlyand J, Snijders AM, Albertson DG. Byrd KN, et al. Among authors: fridlyand j. Breast Cancer Res Treat. 2008 May;109(1):47-54. doi: 10.1007/s10549-007-9623-7. Epub 2007 Jun 23. Breast Cancer Res Treat. 2008. PMID: 17588203
56 results