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Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
Zhao G, Jeoung NH, Burgess SC, Rosaaen-Stowe KA, Inagaki T, Latif S, Shelton JM, McAnally J, Bassel-Duby R, Harris RA, Richardson JA, Kliewer SA. Zhao G, et al. Among authors: burgess sc. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H936-43. doi: 10.1152/ajpheart.00870.2007. Epub 2007 Dec 14. Am J Physiol Heart Circ Physiol. 2008. PMID: 18083902 Free article.
The NQO1 bioactivatable drug, β-lapachone, alters the redox state of NQO1+ pancreatic cancer cells, causing perturbation in central carbon metabolism.
Silvers MA, Deja S, Singh N, Egnatchik RA, Sudderth J, Luo X, Beg MS, Burgess SC, DeBerardinis RJ, Boothman DA, Merritt ME. Silvers MA, et al. Among authors: burgess sc. J Biol Chem. 2017 Nov 3;292(44):18203-18216. doi: 10.1074/jbc.M117.813923. Epub 2017 Sep 15. J Biol Chem. 2017. PMID: 28916726 Free PMC article.
242 results