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Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner N, Treske B, Paquet D, Holmström K, Schiesling C, Gispert S, Carballo-Carbajal I, Berg D, Hoepken HH, Gasser T, Krüger R, Winklhofer KF, Vogel F, Reichert AS, Auburger G, Kahle PJ, Schmid B, Haass C. Exner N, et al. Among authors: holmstrom k. J Neurosci. 2007 Nov 7;27(45):12413-8. doi: 10.1523/JNEUROSCI.0719-07.2007. J Neurosci. 2007. PMID: 17989306 Free PMC article.
Nrf2 regulates ROS production by mitochondria and NADPH oxidase.
Kovac S, Angelova PR, Holmström KM, Zhang Y, Dinkova-Kostova AT, Abramov AY. Kovac S, et al. Biochim Biophys Acta. 2015 Apr;1850(4):794-801. doi: 10.1016/j.bbagen.2014.11.021. Epub 2014 Dec 5. Biochim Biophys Acta. 2015. PMID: 25484314 Free PMC article.
The ins and outs of mitochondrial calcium.
Finkel T, Menazza S, Holmström KM, Parks RJ, Liu J, Sun J, Liu J, Pan X, Murphy E. Finkel T, et al. Circ Res. 2015 May 22;116(11):1810-9. doi: 10.1161/CIRCRESAHA.116.305484. Circ Res. 2015. PMID: 25999421 Free PMC article. Review.
101 results