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Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin.
Exner N, Treske B, Paquet D, Holmström K, Schiesling C, Gispert S, Carballo-Carbajal I, Berg D, Hoepken HH, Gasser T, Krüger R, Winklhofer KF, Vogel F, Reichert AS, Auburger G, Kahle PJ, Schmid B, Haass C. Exner N, et al. J Neurosci. 2007 Nov 7;27(45):12413-8. doi: 10.1523/JNEUROSCI.0719-07.2007. J Neurosci. 2007. PMID: 17989306 Free PMC article.
The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.
Kim H, Calatayud C, Guha S, Fernández-Carasa I, Berkowitz L, Carballo-Carbajal I, Ezquerra M, Fernández-Santiago R, Kapahi P, Raya Á, Miranda-Vizuete A, Lizcano JM, Vila M, Caldwell KA, Caldwell GA, Consiglio A, Dalfo E. Kim H, et al. Among authors: carballo carbajal i. Mol Neurobiol. 2018 Sep;55(9):7533-7552. doi: 10.1007/s12035-018-0881-7. Epub 2018 Feb 10. Mol Neurobiol. 2018. PMID: 29429047 Free PMC article.
Correction to: The Small GTPase RAC1/CED-10 Is Essential in Maintaining Dopaminergic Neuron Function and Survival Against α-Synuclein-Induced Toxicity.
Kim H, Calatayud C, Guha S, Fernández-Carasa I, Berkowitz L, Carballo-Carbajal I, Ezquerra M, Fernández-Santiago R, Kapahi P, Raya Á, Miranda-Vizuete A, Lizcano JM, Vila M, Caldwell KA, Caldwell GA, Consiglio A, Dalfo E. Kim H, et al. Among authors: carballo carbajal i. Mol Neurobiol. 2018 Sep;55(9):7553-7554. doi: 10.1007/s12035-018-1010-3. Mol Neurobiol. 2018. PMID: 29611099 Free PMC article.
Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease.
Sánchez-Danés A, Richaud-Patin Y, Carballo-Carbajal I, Jiménez-Delgado S, Caig C, Mora S, Di Guglielmo C, Ezquerra M, Patel B, Giralt A, Canals JM, Memo M, Alberch J, López-Barneo J, Vila M, Cuervo AM, Tolosa E, Consiglio A, Raya A. Sánchez-Danés A, et al. EMBO Mol Med. 2012 May;4(5):380-95. doi: 10.1002/emmm.201200215. Epub 2012 Mar 8. EMBO Mol Med. 2012. PMID: 22407749 Free PMC article.
Aberrant epigenome in iPSC-derived dopaminergic neurons from Parkinson's disease patients.
Fernández-Santiago R, Carballo-Carbajal I, Castellano G, Torrent R, Richaud Y, Sánchez-Danés A, Vilarrasa-Blasi R, Sánchez-Pla A, Mosquera JL, Soriano J, López-Barneo J, Canals JM, Alberch J, Raya Á, Vila M, Consiglio A, Martín-Subero JI, Ezquerra M, Tolosa E. Fernández-Santiago R, et al. EMBO Mol Med. 2015 Dec;7(12):1529-46. doi: 10.15252/emmm.201505439. EMBO Mol Med. 2015. PMID: 26516212 Free PMC article.
Chitinase 3-like 1 is neurotoxic in primary cultured neurons.
Matute-Blanch C, Calvo-Barreiro L, Carballo-Carbajal I, Gonzalo R, Sanchez A, Vila M, Montalban X, Comabella M. Matute-Blanch C, et al. Among authors: carballo carbajal i. Sci Rep. 2020 Apr 28;10(1):7118. doi: 10.1038/s41598-020-64093-2. Sci Rep. 2020. PMID: 32346016 Free PMC article.
15 results