Fujita J - Search Results

1

Gankyrin oncoprotein overexpression as a critical factor for tumor growth in human esophageal squamous cell carcinoma and its clinical significance.

Ortiz CM, Ito T, Tanaka E, Tsunoda S, Nagayama S, Sakai Y, Higashitsuji H, Fujita J, Shimada Y. Ortiz CM, et al. Among authors: fujita j. Int J Cancer. 2008 Jan 15;122(2):325-32. doi: 10.1002/ijc.23106. Int J Cancer. 2008. PMID: 17935131 Free article.

2

The oncoprotein gankyrin binds to MDM2/HDM2, enhancing ubiquitylation and degradation of p53.

Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Nagao T, Sumitomo Y, Masuda T, Dawson S, Shimada Y, Mayer RJ, Fujita J. Higashitsuji H, et al. Among authors: fujita j. Cancer Cell. 2005 Jul;8(1):75-87. doi: 10.1016/j.ccr.2005.06.006. Cancer Cell. 2005. PMID: 16023600 Free article.

3

The oncoprotein gankyrin negatively regulates both p53 and RB by enhancing proteasomal degradation.

Higashitsuji H, Liu Y, Mayer RJ, Fujita J. Higashitsuji H, et al. Among authors: fujita j. Cell Cycle. 2005 Oct;4(10):1335-7. doi: 10.4161/cc.4.10.2107. Epub 2005 Oct 17. Cell Cycle. 2005. PMID: 16177571

4

Association of gankyrin protein expression with early clinical stages and insulin-like growth factor-binding protein 5 expression in human hepatocellular carcinoma.

Umemura A, Itoh Y, Itoh K, Yamaguchi K, Nakajima T, Higashitsuji H, Onoue H, Fukumoto M, Okanoue T, Fujita J. Umemura A, et al. Among authors: fujita j. Hepatology. 2008 Feb;47(2):493-502. doi: 10.1002/hep.22027. Hepatology. 2008. PMID: 18161051

5

MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity.

Nagao T, Higashitsuji H, Nonoguchi K, Sakurai T, Dawson S, Mayer RJ, Itoh K, Fujita J. Nagao T, et al. Among authors: fujita j. J Biol Chem. 2003 Mar 21;278(12):10668-74. doi: 10.1074/jbc.M206104200. Epub 2003 Jan 13. J Biol Chem. 2003. PMID: 12525503 Free article.

6

Role of a novel oncogenic protein, gankyrin, in hepatocyte proliferation.

Iwai A, Marusawa H, Kiuchi T, Higashitsuji H, Tanaka K, Fujita J, Chiba T. Iwai A, et al. Among authors: fujita j. J Gastroenterol. 2003;38(8):751-8. doi: 10.1007/s00535-003-1141-8. J Gastroenterol. 2003. PMID: 14505129

7

A cleaved form of MAGE-A4 binds to Miz-1 and induces apoptosis in human cells.

Sakurai T, Itoh K, Higashitsuji H, Nagao T, Nonoguchi K, Chiba T, Fujita J. Sakurai T, et al. Among authors: fujita j. J Biol Chem. 2004 Apr 9;279(15):15505-14. doi: 10.1074/jbc.M310437200. Epub 2004 Jan 22. J Biol Chem. 2004. PMID: 14739298 Free article.

8

Gankyrin: a new oncoprotein and regulator of pRb and p53.

Dawson S, Higashitsuji H, Wilkinson AJ, Fujita J, Mayer RJ. Dawson S, et al. Among authors: fujita j. Trends Cell Biol. 2006 May;16(5):229-33. doi: 10.1016/j.tcb.2006.03.001. Epub 2006 Apr 3. Trends Cell Biol. 2006. PMID: 16581249

9

The oncoprotein gankyrin interacts with RelA and suppresses NF-kappaB activity.

Higashitsuji H, Higashitsuji H, Liu Y, Masuda T, Fujita T, Abdel-Aziz HI, Kongkham S, Dawson S, John Mayer R, Itoh Y, Sakurai T, Itoh K, Fujita J. Higashitsuji H, et al. Among authors: fujita j, fujita t. Biochem Biophys Res Commun. 2007 Nov 23;363(3):879-84. doi: 10.1016/j.bbrc.2007.09.072. Epub 2007 Sep 29. Biochem Biophys Res Commun. 2007. PMID: 17904523

10

Overexpression of gankyrin in mouse hepatocytes induces hemangioma by suppressing factor inhibiting hypoxia-inducible factor-1 (FIH-1) and activating hypoxia-inducible factor-1.

Liu Y, Higashitsuji H, Higashitsuji H, Itoh K, Sakurai T, Koike K, Hirota K, Fukumoto M, Fujita J. Liu Y, et al. Among authors: fujita j. Biochem Biophys Res Commun. 2013 Mar 1;432(1):22-7. doi: 10.1016/j.bbrc.2013.01.093. Epub 2013 Feb 1. Biochem Biophys Res Commun. 2013. PMID: 23376718

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