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Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.
MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A. MacMurray AJ, et al. Among authors: lernmark a. Genome Res. 2002 Jul;12(7):1029-39. doi: 10.1101/gr.412702. Genome Res. 2002. PMID: 12097339 Free PMC article.
Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat.
Michalkiewicz M, Michalkiewicz T, Ettinger RA, Rutledge EA, Fuller JM, Moralejo DH, Van Yserloo B, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A. Michalkiewicz M, et al. Among authors: lernmark a. Physiol Genomics. 2004 Oct 4;19(2):228-32. doi: 10.1152/physiolgenomics.00126.2004. Epub 2004 Aug 24. Physiol Genomics. 2004. PMID: 15328390
SUMO4 M55V polymorphism affects susceptibility to type I diabetes in HLA DR3- and DR4-positive Swedish patients.
Sedimbi SK, Luo XR, Sanjeevi CB; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group; Lernmark A, Landin-Olsson M, Arnqvist H, Björck E, Nyström L, Ohlson LO, Scherstén B, Ostman J, Aili M, Bååth LE, Carlsson E, Edenwall H, Forsander G, Granström BW, Gustavsson I, Hanås R, Hellenberg L, Hellgren H, Holmberg E, Hörnell H, Ivarsson SA, Johansson C, Jonsell G, Kockum K, Lindblad B, Lindh A, Ludvigsson J, Myrdal U, Neiderud J, Segnestam K, Sjöblad S, Skogsberg L, Strömberg L, Ståhle U, Thalme B, Tullus K, Tuvemo T, Wallensteen M, Westphal O, Dahlquist G, Aman J. Sedimbi SK, et al. Among authors: lernmark a. Genes Immun. 2007 Sep;8(6):518-21. doi: 10.1038/sj.gene.6364406. Epub 2007 Jun 7. Genes Immun. 2007. PMID: 17554341
Annual screening detects celiac disease in children with type 1 diabetes.
Larsson K, Carlsson A, Cederwall E, Jönsson B, Neiderud J, Jonsson B, Lernmark A, Ivarsson SA; Skåne Study Group. Larsson K, et al. Among authors: lernmark a. Pediatr Diabetes. 2008 Aug;9(4 Pt 2):354-9. doi: 10.1111/j.1399-5448.2008.00367.x. Pediatr Diabetes. 2008. PMID: 18774995
Sequence variation and expression of the Gimap gene family in the BB rat.
Rutledge EA, Fuller JM, Van Yserloo B, Moralejo DH, Ettinger RA, Gaur P, Hoehna JL, Peterson MR, Jensen R, Kwitek AE, Lernmark A. Rutledge EA, et al. Among authors: lernmark a. Exp Diabetes Res. 2009;2009:835650. doi: 10.1155/2009/835650. Epub 2009 May 3. Exp Diabetes Res. 2009. PMID: 19421422 Free PMC article.
Type 1 diabetes patients born to immigrants to Sweden increase their native diabetes risk and differ from Swedish patients in HLA types and islet autoantibodies.
Delli AJ, Lindblad B, Carlsson A, Forsander G, Ivarsson SA, Ludvigsson J, Marcus C, Lernmark A; Better Diabetes Diagnosis (BDD) Study Group. Delli AJ, et al. Among authors: lernmark a. Pediatr Diabetes. 2010 Dec;11(8):513-20. doi: 10.1111/j.1399-5448.2010.00637.x. Pediatr Diabetes. 2010. PMID: 20337975
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