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Opioid and melanocortin receptors: do they have overlapping pharmacophores?
Lee YS, Agnes RS, Cain JP, Kulkarni V, Cai M, Salibay C, Ciano K, Petrov R, Mayorov A, Vagner J, Trivedi D, Davis P, Ma SW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Lee YS, et al. Among authors: kulkarni v. Biopolymers. 2008;90(3):433-8. doi: 10.1002/bip.20814. Biopolymers. 2008. PMID: 17657709 Free PMC article.
Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities.
Nair P, Yamamoto T, Largent-Milnes TM, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Nair P, et al. Among authors: kulkarni v. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4975-8. doi: 10.1016/j.bmcl.2013.06.065. Epub 2013 Jul 2. Bioorg Med Chem Lett. 2013. PMID: 23899615 Free PMC article.
Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities.
Nair P, Yamamoto T, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Nair P, et al. Among authors: kulkarni v. Bioorg Med Chem Lett. 2015 Sep 1;25(17):3716-20. doi: 10.1016/j.bmcl.2015.06.030. Epub 2015 Jun 15. Bioorg Med Chem Lett. 2015. PMID: 26212775 Free PMC article.
Novel bifunctional peptides as opioid agonists and NK-1 antagonists.
Nair P, Yamamoto T, Kulkarni V, Moye S, Navratilova E, Davis P, Largent T, Ma SW, Yamamura HI, Vanderah T, Lai J, Porreca F, Hruby VJ. Nair P, et al. Among authors: kulkarni v. Adv Exp Med Biol. 2009;611:537-8. doi: 10.1007/978-0-387-73657-0_235. Adv Exp Med Biol. 2009. PMID: 19400302 Free PMC article. No abstract available.
Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands.
Deekonda S, Wugalter L, Kulkarni V, Rankin D, Largent-Milnes TM, Davis P, Bassirirad NM, Lai J, Vanderah TW, Porreca F, Hruby VJ. Deekonda S, et al. Among authors: kulkarni v. Bioorg Med Chem. 2015 Sep 15;23(18):6185-94. doi: 10.1016/j.bmc.2015.07.071. Epub 2015 Aug 4. Bioorg Med Chem. 2015. PMID: 26299827 Free PMC article.
Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives.
Deekonda S, Wugalter L, Rankin D, Largent-Milnes TM, Davis P, Wang Y, Bassirirad NM, Lai J, Kulkarni V, Vanderah TW, Porreca F, Hruby VJ. Deekonda S, et al. Among authors: kulkarni v. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4683-8. doi: 10.1016/j.bmcl.2015.07.064. Epub 2015 Jul 29. Bioorg Med Chem Lett. 2015. PMID: 26323872 Free PMC article.
909 results