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Expression of the heparan sulfate-degrading enzyme heparanase is induced in infiltrating CD4+ T cells in experimental autoimmune encephalomyelitis and regulated at the level of transcription by early growth response gene 1.
de Mestre AM, Staykova MA, Hornby JR, Willenborg DO, Hulett MD. de Mestre AM, et al. Among authors: willenborg do. J Leukoc Biol. 2007 Nov;82(5):1289-300. doi: 10.1189/jlb.0507315. Epub 2007 Jul 26. J Leukoc Biol. 2007. PMID: 17656651
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