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From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae.
Chem Biol Drug Des. 2007 Jun;69(6):395-404. doi: 10.1111/j.1747-0285.2007.00521.x.
Chem Biol Drug Des. 2007.
PMID: 17581233
Novel approach to mapping of resistance mutations in whole genomes by using restriction enzyme modulation of transformation efficiency.
Lerner CG, Kakavas SJ, Wagner C, Chang RT, Merta PJ, Ruan X, Metzger RE, Beutel BA.
Lerner CG, et al. Among authors: kakavas sj.
Antimicrob Agents Chemother. 2005 Jul;49(7):2767-77. doi: 10.1128/AAC.49.7.2767-2777.2005.
Antimicrob Agents Chemother. 2005.
PMID: 15980348
Free PMC article.
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Novel antibacterial class.
Dandliker PJ, Pratt SD, Nilius AM, Black-Schaefer C, Ruan X, Towne DL, Clark RF, Englund EE, Wagner R, Weitzberg M, Chovan LE, Hickman RK, Daly MM, Kakavas S, Zhong P, Cao Z, David CA, Xuei X, Lerner CG, Soni NB, Bui M, Shen LL, Cai Y, Merta PJ, Saiki AY, Beutel BA.
Dandliker PJ, et al.
Antimicrob Agents Chemother. 2003 Dec;47(12):3831-9. doi: 10.1128/AAC.47.12.3831-3839.2003.
Antimicrob Agents Chemother. 2003.
PMID: 14638491
Free PMC article.
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Acyltransferase domain substitutions in erythromycin polyketide synthase yield novel erythromycin derivatives.
Ruan X, Pereda A, Stassi DL, Zeidner D, Summers RG, Jackson M, Shivakumar A, Kakavas S, Staver MJ, Donadio S, Katz L.
Ruan X, et al.
J Bacteriol. 1997 Oct;179(20):6416-25. doi: 10.1128/jb.179.20.6416-6425.1997.
J Bacteriol. 1997.
PMID: 9335291
Free PMC article.
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Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering.
Stassi DL, Kakavas SJ, Reynolds KA, Gunawardana G, Swanson S, Zeidner D, Jackson M, Liu H, Buko A, Katz L.
Stassi DL, et al. Among authors: kakavas sj.
Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7305-9. doi: 10.1073/pnas.95.13.7305.
Proc Natl Acad Sci U S A. 1998.
PMID: 9636144
Free PMC article.
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Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis.
Kakavas SJ, Katz L, Stassi D.
Kakavas SJ, et al.
J Bacteriol. 1997 Dec;179(23):7515-22. doi: 10.1128/jb.179.23.7515-7522.1997.
J Bacteriol. 1997.
PMID: 9393718
Free PMC article.
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Small Molecule IL-36γ Antagonist as a Novel Therapeutic Approach for Plaque Psoriasis.
Todorović V, Su Z, Putman CB, Kakavas SJ, Salte KM, McDonald HA, Wetter JB, Paulsboe SE, Sun Q, Gerstein CE, Medina L, Sielaff B, Sadhukhan R, Stockmann H, Richardson PL, Qiu W, Argiriadi MA, Henry RF, Herold JM, Shotwell JB, McGaraughty SP, Honore P, Gopalakrishnan SM, Sun CC, Scott VE.
Todorović V, et al. Among authors: kakavas sj.
Sci Rep. 2019 Jun 24;9(1):9089. doi: 10.1038/s41598-019-45626-w.
Sci Rep. 2019.
PMID: 31235749
Free PMC article.
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Solution structure and function of an essential CMP kinase of Streptococcus pneumoniae.
Yu L, Mack J, Hajduk PJ, Kakavas SJ, Saiki AY, Lerner CG, Olejniczak ET.
Yu L, et al. Among authors: kakavas sj.
Protein Sci. 2003 Nov;12(11):2613-21. doi: 10.1110/ps.03256803.
Protein Sci. 2003.
PMID: 14573872
Free PMC article.
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