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From bacterial genomes to novel antibacterial agents: discovery, characterization, and antibacterial activity of compounds that bind to HI0065 (YjeE) from Haemophilus influenzae.
Lerner CG, Hajduk PJ, Wagner R, Wagenaar FL, Woodall C, Gu YG, Searle XB, Florjancic AS, Zhang T, Clark RF, Cooper CS, Mack JC, Yu L, Cai M, Betz SF, Chovan LE, McCall JO, Black-Schaefer CL, Kakavas SJ, Schurdak ME, Comess KM, Walter KA, Edalji R, Dorwin SA, Smith RA, Hebert EJ, Harlan JE, Metzger RE, Merta PJ, Baranowski JL, Coen ML, Thornewell SJ, Shivakumar AG, Saiki AY, Soni N, Bui M, Balli DJ, Sanders WJ, Nilius AM, Holzman TF, Fesik SW, Beutel BA. Lerner CG, et al. Among authors: cooper cs. Chem Biol Drug Des. 2007 Jun;69(6):395-404. doi: 10.1111/j.1747-0285.2007.00521.x. Chem Biol Drug Des. 2007. PMID: 17581233
Structure-activity relationships of novel potent MurF inhibitors.
Gu YG, Florjancic AS, Clark RF, Zhang T, Cooper CS, Anderson DD, Lerner CG, McCall JO, Cai Y, Black-Schaefer CL, Stamper GF, Hajduk PJ, Beutel BA. Gu YG, et al. Among authors: cooper cs. Bioorg Med Chem Lett. 2004 Jan 5;14(1):267-70. doi: 10.1016/j.bmcl.2003.09.073. Bioorg Med Chem Lett. 2004. PMID: 14684340
Structure-based optimization of MurF inhibitors.
Stamper GF, Longenecker KL, Fry EH, Jakob CG, Florjancic AS, Gu YG, Anderson DD, Cooper CS, Zhang T, Clark RF, Cia Y, Black-Schaefer CL, Owen McCall J, Lerner CG, Hajduk PJ, Beutel BA, Stoll VS. Stamper GF, et al. Among authors: cooper cs. Chem Biol Drug Des. 2006 Jan;67(1):58-65. doi: 10.1111/j.1747-0285.2005.00317.x. Chem Biol Drug Des. 2006. PMID: 16492149
Synthesis and structure-activity relationships of 2-pyridones: a novel series of potent DNA gyrase inhibitors as antibacterial agents.
Li Q, Chu DT, Claiborne A, Cooper CS, Lee CM, Raye K, Berst KB, Donner P, Wang W, Hasvold L, Fung A, Ma Z, Tufano M, Flamm R, Shen LL, Baranowski J, Nilius A, Alder J, Meulbroek J, Marsh K, Crowell D, Hui Y, Seif L, Melcher LM, Plattner JJ, et al. Li Q, et al. Among authors: cooper cs. J Med Chem. 1996 Aug 2;39(16):3070-88. doi: 10.1021/jm960207w. J Med Chem. 1996. PMID: 8759628
439 results