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Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.
Maser RS, Choudhury B, Campbell PJ, Feng B, Wong KK, Protopopov A, O'Neil J, Gutierrez A, Ivanova E, Perna I, Lin E, Mani V, Jiang S, McNamara K, Zaghlul S, Edkins S, Stevens C, Brennan C, Martin ES, Wiedemeyer R, Kabbarah O, Nogueira C, Histen G, Aster J, Mansour M, Duke V, Foroni L, Fielding AK, Goldstone AH, Rowe JM, Wang YA, Look AT, Stratton MR, Chin L, Futreal PA, DePinho RA. Maser RS, et al. Among authors: depinho ra. Nature. 2007 Jun 21;447(7147):966-71. doi: 10.1038/nature05886. Epub 2007 May 21. Nature. 2007. PMID: 17515920 Free PMC article.
Malignant melanoma: modern black plague and genetic black box.
Chin L, Merlino G, DePinho RA. Chin L, et al. Among authors: depinho ra. Genes Dev. 1998 Nov 15;12(22):3467-81. doi: 10.1101/gad.12.22.3467. Genes Dev. 1998. PMID: 9832500 Free article. Review. No abstract available.
Essential role for oncogenic Ras in tumour maintenance.
Chin L, Tam A, Pomerantz J, Wong M, Holash J, Bardeesy N, Shen Q, O'Hagan R, Pantginis J, Zhou H, Horner JW 2nd, Cordon-Cardo C, Yancopoulos GD, DePinho RA. Chin L, et al. Among authors: depinho ra. Nature. 1999 Jul 29;400(6743):468-72. doi: 10.1038/22788. Nature. 1999. PMID: 10440378
461 results