Phillips C - Search Results

1

Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines.

Fish PV, Barber CG, Brown DG, Butt R, Collis MG, Dickinson RP, Henry BT, Horne VA, Huggins JP, King E, O'Gara M, McCleverty D, McIntosh F, Phillips C, Webster R. Fish PV, et al. Among authors: phillips c. J Med Chem. 2007 May 17;50(10):2341-51. doi: 10.1021/jm061066t. Epub 2007 Apr 21. J Med Chem. 2007. PMID: 17447747

2

Identification, synthesis and SAR of amino substituted pyrido[3,2b]pyrazinones as potent and selective PDE5 inhibitors.

Owen DR, Walker JK, Jon Jacobsen E, Freskos JN, Hughes RO, Brown DL, Bell AS, Brown DG, Phillips C, Mischke BV, Molyneaux JM, Fobian YM, Heasley SE, Moon JB, Stallings WC, Joseph Rogier D, Fox DN, Palmer MJ, Ringer T, Rodriquez-Lens M, Cubbage JW, Blevis-Bal RM, Benson AG, Acker BA, Maddux TM, Tollefson MB, Bond BR, Macinnes A, Yu Y. Owen DR, et al. Among authors: phillips c. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4088-91. doi: 10.1016/j.bmcl.2009.06.012. Epub 2009 Jun 6. Bioorg Med Chem Lett. 2009. PMID: 19540112 Free article.

3

Novel indazole non-nucleoside reverse transcriptase inhibitors using molecular hybridization based on crystallographic overlays.

Jones LH, Allan G, Barba O, Burt C, Corbau R, Dupont T, Knöchel T, Irving S, Middleton DS, Mowbray CE, Perros M, Ringrose H, Swain NA, Webster R, Westby M, Phillips C. Jones LH, et al. Among authors: phillips c. J Med Chem. 2009 Feb 26;52(4):1219-23. doi: 10.1021/jm801322h. J Med Chem. 2009. PMID: 19175319

4

Computational tools for the analysis and visualization of multiple protein-ligand complexes.

O'Brien SE, Brown DG, Mills JE, Phillips C, Morris G. O'Brien SE, et al. Among authors: phillips c. J Mol Graph Model. 2005 Dec;24(3):186-94. doi: 10.1016/j.jmgm.2005.08.003. Epub 2005 Sep 19. J Mol Graph Model. 2005. PMID: 16169759

5

Design and synthesis of inhaled p38 inhibitors for the treatment of chronic obstructive pulmonary disease.

Millan DS, Bunnage ME, Burrows JL, Butcher KJ, Dodd PG, Evans TJ, Fairman DA, Hughes SJ, Kilty IC, Lemaitre A, Lewthwaite RA, Mahnke A, Mathias JP, Philip J, Smith RT, Stefaniak MH, Yeadon M, Phillips C. Millan DS, et al. Among authors: phillips c. J Med Chem. 2011 Nov 24;54(22):7797-814. doi: 10.1021/jm200677b. Epub 2011 Oct 28. J Med Chem. 2011. PMID: 21888439

6

Sulfonamides as selective oestrogen receptor β agonists.

Roberts LR, Armor D, Barker C, Bent A, Bess K, Brown A, Favor DA, Ellis D, Irving SL, MacKenny M, Phillips C, Pullen N, Stennett A, Strand L, Styles M. Roberts LR, et al. Among authors: phillips c. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5680-3. doi: 10.1016/j.bmcl.2011.08.041. Epub 2011 Aug 16. Bioorg Med Chem Lett. 2011. PMID: 21885279

7

Synthesis and evaluation of heteroarylalanine diacids as potent and selective neutral endopeptidase inhibitors.

Glossop MS, Bazin RJ, Dack KN, Fox DN, MacDonald GA, Mills M, Owen DR, Phillips C, Reeves KA, Ringer TJ, Strang RS, Watson CA. Glossop MS, et al. Among authors: phillips c. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3404-6. doi: 10.1016/j.bmcl.2011.03.109. Epub 2011 Apr 5. Bioorg Med Chem Lett. 2011. PMID: 21515054

8

Design and structure of stapled peptides binding to estrogen receptors.

Phillips C, Roberts LR, Schade M, Bazin R, Bent A, Davies NL, Moore R, Pannifer AD, Pickford AR, Prior SH, Read CM, Scott A, Brown DG, Xu B, Irving SL. Phillips C, et al. J Am Chem Soc. 2011 Jun 29;133(25):9696-9. doi: 10.1021/ja202946k. Epub 2011 Jun 6. J Am Chem Soc. 2011. PMID: 21612236

9

TAK1 inhibition in the DFG-out conformation.

Kilty I, Green MP, Bell AS, Brown DG, Dodd PG, Hewson C, Hughes SJ, Phillips C, Ryckmans T, Smith RT, van Hoorn WP, Cohen P, Jones LH. Kilty I, et al. Among authors: phillips c. Chem Biol Drug Des. 2013 Nov;82(5):500-5. doi: 10.1111/cbdd.12169. Chem Biol Drug Des. 2013. PMID: 23745990

10

Regulatory roles of the N-terminal domain based on crystal structures of human pyruvate dehydrogenase kinase 2 containing physiological and synthetic ligands.

Knoechel TR, Tucker AD, Robinson CM, Phillips C, Taylor W, Bungay PJ, Kasten SA, Roche TE, Brown DG. Knoechel TR, et al. Among authors: phillips c. Biochemistry. 2006 Jan 17;45(2):402-15. doi: 10.1021/bi051402s. Biochemistry. 2006. PMID: 16401071

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