Huggins JP - Search Results

1

Selective urokinase-type plasminogen activator inhibitors. 4. 1-(7-sulfonamidoisoquinolinyl)guanidines.

Fish PV, Barber CG, Brown DG, Butt R, Collis MG, Dickinson RP, Henry BT, Horne VA, Huggins JP, King E, O'Gara M, McCleverty D, McIntosh F, Phillips C, Webster R. Fish PV, et al. Among authors: huggins jp. J Med Chem. 2007 May 17;50(10):2341-51. doi: 10.1021/jm061066t. Epub 2007 Apr 21. J Med Chem. 2007. PMID: 17447747

2

A potent, selective inhibitor of matrix metalloproteinase-3 for the topical treatment of chronic dermal ulcers.

Fray MJ, Dickinson RP, Huggins JP, Occleston NL. Fray MJ, et al. Among authors: huggins jp. J Med Chem. 2003 Jul 31;46(16):3514-25. doi: 10.1021/jm0308038. J Med Chem. 2003. PMID: 12877590

3

Assessment of the pharmacology and tolerability of PF-04457845, an irreversible inhibitor of fatty acid amide hydrolase-1, in healthy subjects.

Li GL, Winter H, Arends R, Jay GW, Le V, Young T, Huggins JP. Li GL, et al. Among authors: huggins jp. Br J Clin Pharmacol. 2012 May;73(5):706-16. doi: 10.1111/j.1365-2125.2011.04137.x. Br J Clin Pharmacol. 2012. PMID: 22044402 Free PMC article. Clinical Trial.

4

An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee.

Huggins JP, Smart TS, Langman S, Taylor L, Young T. Huggins JP, et al. Pain. 2012 Sep;153(9):1837-1846. doi: 10.1016/j.pain.2012.04.020. Epub 2012 Jun 21. Pain. 2012. PMID: 22727500 Clinical Trial.

5

Antiviral activity of cyclopentenyl nucleosides against orthopox viruses (Smallpox, monkeypox and cowpox).

Chu CK, Jin YH, Baker RO, Huggins J. Chu CK, et al. Bioorg Med Chem Lett. 2003 Jan 6;13(1):9-12. doi: 10.1016/s0960-894x(02)00841-7. Bioorg Med Chem Lett. 2003. PMID: 12467606 Free PMC article.

6

Effects of gabapentin on experimental somatic pain and temporal summation.

Arendt-Nielsen L, Frøkjaer JB, Staahl C, Graven-Nielsen T, Huggins JP, Smart TS, Drewes AM. Arendt-Nielsen L, et al. Among authors: huggins jp. Reg Anesth Pain Med. 2007 Sep-Oct;32(5):382-8. doi: 10.1016/j.rapm.2007.05.002. Reg Anesth Pain Med. 2007. PMID: 17961835 Clinical Trial.

7

Pharmacological modulation of pain-related brain activity during normal and central sensitization states in humans.

Iannetti GD, Zambreanu L, Wise RG, Buchanan TJ, Huggins JP, Smart TS, Vennart W, Tracey I. Iannetti GD, et al. Among authors: huggins jp. Proc Natl Acad Sci U S A. 2005 Dec 13;102(50):18195-200. doi: 10.1073/pnas.0506624102. Epub 2005 Dec 5. Proc Natl Acad Sci U S A. 2005. PMID: 16330766 Free PMC article. Clinical Trial.

8

Disambiguating pharmacological mechanisms from placebo in neuropathic pain using functional neuroimaging.

Wanigasekera V, Wartolowska K, Huggins JP, Duff EP, Vennart W, Whitlock M, Massat N, Pauer L, Rogers P, Hoggart B, Tracey I. Wanigasekera V, et al. Among authors: huggins jp. Br J Anaesth. 2018 Feb;120(2):299-307. doi: 10.1016/j.bja.2017.11.064. Epub 2017 Nov 21. Br J Anaesth. 2018. PMID: 29406179 Free article. Clinical Trial.

9

Pharmacologic modulation of hand pain in osteoarthritis: a double-blind placebo-controlled functional magnetic resonance imaging study using naproxen.

Sanders D, Krause K, O'Muircheartaigh J, Thacker MA, Huggins JP, Vennart W, Massat NJ, Choy E, Williams SC, Howard MA. Sanders D, et al. Among authors: huggins jp. Arthritis Rheumatol. 2015 Mar;67(3):741-51. doi: 10.1002/art.38987. Arthritis Rheumatol. 2015. PMID: 25533872 Free PMC article. Clinical Trial.

10

Pregabalin rectifies aberrant brain chemistry, connectivity, and functional response in chronic pain patients.

Harris RE, Napadow V, Huggins JP, Pauer L, Kim J, Hampson J, Sundgren PC, Foerster B, Petrou M, Schmidt-Wilcke T, Clauw DJ. Harris RE, et al. Among authors: huggins jp. Anesthesiology. 2013 Dec;119(6):1453-64. doi: 10.1097/ALN.0000000000000017. Anesthesiology. 2013. PMID: 24343290 Free article. Clinical Trial.

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