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Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramides.
Pryde DC, Maw GN, Planken S, Platts MY, Sanderson V, Corless M, Stobie A, Barber CG, Russell R, Foster L, Barker L, Wayman C, Van Der Graaf P, Stacey P, Morren D, Kohl C, Beaumont K, Coggon S, Tute M. Pryde DC, et al. Among authors: barber cg. J Med Chem. 2006 Jul 13;49(14):4409-24. doi: 10.1021/jm060133g. J Med Chem. 2006. PMID: 16821800
The design and discovery of novel amide CCR5 antagonists.
Pryde DC, Corless M, Fenwick DR, Mason HJ, Stammen BC, Stephenson PT, Ellis D, Bachelor D, Gordon D, Barber CG, Wood A, Middleton DS, Blakemore DC, Parsons GC, Eastwood R, Platts MY, Statham K, Paradowski KA, Burt C, Klute W. Pryde DC, et al. Among authors: barber cg. Bioorg Med Chem Lett. 2009 Feb 15;19(4):1084-8. doi: 10.1016/j.bmcl.2009.01.012. Epub 2009 Jan 10. Bioorg Med Chem Lett. 2009. PMID: 19167884
The discovery of UK-369003, a novel PDE5 inhibitor with the potential for oral bioavailability and dose-proportional pharmacokinetics.
Rawson DJ, Ballard S, Barber C, Barker L, Beaumont K, Bunnage M, Cole S, Corless M, Denton S, Ellis D, Floc'h M, Foster L, Gosset J, Holmwood F, Lane C, Leahy D, Mathias J, Maw G, Million W, Poinsard C, Price J, Russel R, Street S, Watson L. Rawson DJ, et al. Bioorg Med Chem. 2012 Jan 1;20(1):498-509. doi: 10.1016/j.bmc.2011.10.022. Epub 2011 Oct 24. Bioorg Med Chem. 2012. PMID: 22100260
40 results