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Prototypic long pentraxin PTX3 is present in breast milk, spreads in tissues, and protects neonate mice from Pseudomonas aeruginosa lung infection.
Jaillon S, Mancuso G, Hamon Y, Beauvillain C, Cotici V, Midiri A, Bottazzi B, Nebuloni M, Garlanda C, Frémaux I, Gauchat JF, Descamps P, Beninati C, Mantovani A, Jeannin P, Delneste Y. Jaillon S, et al. Among authors: fremaux i. J Immunol. 2013 Aug 15;191(4):1873-82. doi: 10.4049/jimmunol.1201642. Epub 2013 Jul 17. J Immunol. 2013. PMID: 23863905
IL-34 and macrophage colony-stimulating factor are overexpressed in hepatitis C virus fibrosis and induce profibrotic macrophages that promote collagen synthesis by hepatic stellate cells.
Preisser L, Miot C, Le Guillou-Guillemette H, Beaumont E, Foucher ED, Garo E, Blanchard S, Frémaux I, Croué A, Fouchard I, Lunel-Fabiani F, Boursier J, Roingeard P, Calès P, Delneste Y, Jeannin P. Preisser L, et al. Among authors: fremaux i. Hepatology. 2014 Dec;60(6):1879-90. doi: 10.1002/hep.27328. Epub 2014 Oct 29. Hepatology. 2014. PMID: 25066464
Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression.
Doz E, Rose S, Court N, Front S, Vasseur V, Charron S, Gilleron M, Puzo G, Fremaux I, Delneste Y, Erard F, Ryffel B, Martin OR, Quesniaux VF. Doz E, et al. Among authors: fremaux i. J Biol Chem. 2009 Aug 28;284(35):23187-96. doi: 10.1074/jbc.M109.037846. Epub 2009 Jun 26. J Biol Chem. 2009. PMID: 19561082 Free PMC article.
23 results