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N-(3-(4-Hydroxyphenyl)-propenoyl)-amino acid tryptamides as SIRT2 inhibitors.
Kiviranta PH, Leppänen J, Rinne VM, Suuronen T, Kyrylenko O, Kyrylenko S, Kuusisto E, Tervo AJ, Järvinen T, Salminen A, Poso A, Wallén EA. Kiviranta PH, et al. Among authors: suuronen t. Bioorg Med Chem Lett. 2007 May 1;17(9):2448-51. doi: 10.1016/j.bmcl.2007.02.023. Epub 2007 Feb 13. Bioorg Med Chem Lett. 2007. PMID: 17329104
Oxadiazole-carbonylaminothioureas as SIRT1 and SIRT2 inhibitors.
Huhtiniemi T, Suuronen T, Rinne VM, Wittekindt C, Lahtela-Kakkonen M, Jarho E, Wallén EA, Salminen A, Poso A, Leppänen J. Huhtiniemi T, et al. Among authors: suuronen t. J Med Chem. 2008 Aug 14;51(15):4377-80. doi: 10.1021/jm800639h. Epub 2008 Jul 22. J Med Chem. 2008. PMID: 18642893
N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2.
Huhtiniemi T, Suuronen T, Lahtela-Kakkonen M, Bruijn T, Jääskeläinen S, Poso A, Salminen A, Leppänen J, Jarho E. Huhtiniemi T, et al. Among authors: suuronen t. Bioorg Med Chem. 2010 Aug 1;18(15):5616-25. doi: 10.1016/j.bmc.2010.06.035. Epub 2010 Jun 17. Bioorg Med Chem. 2010. PMID: 20630764
Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2.
Huhtiniemi T, Salo HS, Suuronen T, Poso A, Salminen A, Leppänen J, Jarho E, Lahtela-Kakkonen M. Huhtiniemi T, et al. Among authors: suuronen t. J Med Chem. 2011 Oct 13;54(19):6456-68. doi: 10.1021/jm200590k. Epub 2011 Sep 7. J Med Chem. 2011. PMID: 21895016
58 results