Smith KM - Search Results

1

Conformation-sensitive antibodies against alzheimer amyloid-beta by immunization with a thioredoxin-constrained B-cell epitope peptide.

Moretto N, Bolchi A, Rivetti C, Imbimbo BP, Villetti G, Pietrini V, Polonelli L, Del Signore S, Smith KM, Ferrante RJ, Ottonello S. Moretto N, et al. Among authors: smith km. J Biol Chem. 2007 Apr 13;282(15):11436-45. doi: 10.1074/jbc.M609690200. Epub 2007 Jan 31. J Biol Chem. 2007. PMID: 17267402 Free article.

2

Dose ranging and efficacy study of high-dose coenzyme Q10 formulations in Huntington's disease mice.

Smith KM, Matson S, Matson WR, Cormier K, Del Signore SJ, Hagerty SW, Stack EC, Ryu H, Ferrante RJ. Smith KM, et al. Biochim Biophys Acta. 2006 Jun;1762(6):616-26. doi: 10.1016/j.bbadis.2006.03.004. Epub 2006 Apr 17. Biochim Biophys Acta. 2006. PMID: 16647250 Free article.

3

Modulation of nucleosome dynamics in Huntington's disease.

Stack EC, Del Signore SJ, Luthi-Carter R, Soh BY, Goldstein DR, Matson S, Goodrich S, Markey AL, Cormier K, Hagerty SW, Smith K, Ryu H, Ferrante RJ. Stack EC, et al. Hum Mol Genet. 2007 May 15;16(10):1164-75. doi: 10.1093/hmg/ddm064. Epub 2007 Apr 2. Hum Mol Genet. 2007. PMID: 17403718 Free article.

4

Chronology of behavioral symptoms and neuropathological sequela in R6/2 Huntington's disease transgenic mice.

Stack EC, Kubilus JK, Smith K, Cormier K, Del Signore SJ, Guelin E, Ryu H, Hersch SM, Ferrante RJ. Stack EC, et al. J Comp Neurol. 2005 Oct 3;490(4):354-70. doi: 10.1002/cne.20680. J Comp Neurol. 2005. PMID: 16127709

5

Combination therapy using minocycline and coenzyme Q10 in R6/2 transgenic Huntington's disease mice.

Stack EC, Smith KM, Ryu H, Cormier K, Chen M, Hagerty SW, Del Signore SJ, Cudkowicz ME, Friedlander RM, Ferrante RJ. Stack EC, et al. Among authors: smith km. Biochim Biophys Acta. 2006 Mar;1762(3):373-80. doi: 10.1016/j.bbadis.2005.11.002. Epub 2005 Dec 5. Biochim Biophys Acta. 2006. PMID: 16364609 Free article.

6

Therapeutic attenuation of mitochondrial dysfunction and oxidative stress in neurotoxin models of Parkinson's disease.

Stack EC, Ferro JL, Kim J, Del Signore SJ, Goodrich S, Matson S, Hunt BB, Cormier K, Smith K, Matson WR, Ryu H, Ferrante RJ. Stack EC, et al. Biochim Biophys Acta. 2008 Mar;1782(3):151-62. doi: 10.1016/j.bbadis.2007.12.006. Epub 2008 Jan 16. Biochim Biophys Acta. 2008. PMID: 18206128 Free article.

7

Combined riluzole and sodium phenylbutyrate therapy in transgenic amyotrophic lateral sclerosis mice.

Del Signore SJ, Amante DJ, Kim J, Stack EC, Goodrich S, Cormier K, Smith K, Cudkowicz ME, Ferrante RJ. Del Signore SJ, et al. Amyotroph Lateral Scler. 2009 Apr;10(2):85-94. doi: 10.1080/17482960802226148. Amyotroph Lateral Scler. 2009. PMID: 18618304

8

ADME-guided design and synthesis of aryloxanyl pyrazolone derivatives to block mutant superoxide dismutase 1 (SOD1) cytotoxicity and protein aggregation: potential application for the treatment of amyotrophic lateral sclerosis.

Chen T, Benmohamed R, Kim J, Smith K, Amante D, Morimoto RI, Kirsch DR, Ferrante RJ, Silverman RB. Chen T, et al. J Med Chem. 2012 Jan 12;55(1):515-27. doi: 10.1021/jm2014277. Epub 2011 Dec 22. J Med Chem. 2012. PMID: 22191331 Free PMC article.

9

Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.

Stack EC, Dedeoglu A, Smith KM, Cormier K, Kubilus JK, Bogdanov M, Matson WR, Yang L, Jenkins BG, Luthi-Carter R, Kowall NW, Hersch SM, Beal MF, Ferrante RJ. Stack EC, et al. Among authors: smith km. J Neurosci. 2007 Nov 21;27(47):12908-15. doi: 10.1523/JNEUROSCI.4318-07.2007. J Neurosci. 2007. PMID: 18032664 Free PMC article.

10

Nortriptyline delays disease onset in models of chronic neurodegeneration.

Wang H, Guan Y, Wang X, Smith K, Cormier K, Zhu S, Stavrovskaya IG, Huo C, Ferrante RJ, Kristal BS, Friedlander RM. Wang H, et al. Eur J Neurosci. 2007 Aug;26(3):633-41. doi: 10.1111/j.1460-9568.2007.05663.x. Eur J Neurosci. 2007. PMID: 17686041

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