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Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 2. Synthesis and structure-activity relationships of alpha,alpha-cycloalkylglycine sulfonamides.
Fattori D, Rossi C, Fincham CI, Caciagli V, Catrambone F, D'Andrea P, Felicetti P, Gensini M, Marastoni E, Nannicini R, Paris M, Terracciano R, Bressan A, Giuliani S, Maggi CA, Meini S, Valenti C, Quartara L. Fattori D, et al. Among authors: giuliani s. J Med Chem. 2007 Feb 8;50(3):550-65. doi: 10.1021/jm061143k. J Med Chem. 2007. PMID: 17266207
Insertion of an aspartic acid moiety into cyclic pseudopeptides: synthesis and biological characterization of potent antagonists for the human Tachykinin NK-2 receptor.
Fedi V, Altamura M, Balacco G, Canfarini F, Criscuoli M, Giannotti D, Giolitti A, Giuliani S, Guidi A, Harmat NJ, Nannicini R, Pasqui F, Patacchini R, Perrotta E, Tramontana M, Triolo A, Maggi CA. Fedi V, et al. Among authors: giuliani s. J Med Chem. 2004 Dec 30;47(27):6935-47. doi: 10.1021/jm040832y. J Med Chem. 2004. PMID: 15615542
MEN16132, a novel potent and selective nonpeptide kinin B2 receptor antagonist: in vivo activity on bradykinin-induced bronchoconstriction and nasal mucosa microvascular leakage in anesthetized guinea pigs.
Valenti C, Cialdai C, Giuliani S, Lecci A, Tramontana M, Meini S, Quartara L, Maggi CA. Valenti C, et al. Among authors: giuliani s. J Pharmacol Exp Ther. 2005 Nov;315(2):616-23. doi: 10.1124/jpet.105.088252. Epub 2005 Jul 18. J Pharmacol Exp Ther. 2005. PMID: 16027229
MEN16132, a novel potent and selective nonpeptide antagonist for the human bradykinin B2 receptor. In vitro pharmacology and molecular characterization.
Cucchi P, Meini S, Bressan A, Catalani C, Bellucci F, Santicioli P, Lecci A, Faiella A, Rotondaro L, Giuliani S, Giolitti A, Quartara L, Maggi CA. Cucchi P, et al. Among authors: giuliani s. Eur J Pharmacol. 2005 Dec 28;528(1-3):7-16. doi: 10.1016/j.ejphar.2005.10.014. Epub 2005 Dec 1. Eur J Pharmacol. 2005. PMID: 16324696
Design and synthesis of novel sulfonamide-containing bradykinin hB2 receptor antagonists. 1. Synthesis and SAR of alpha,alpha-dimethylglycine sulfonamides.
Fattori D, Rossi C, Fincham CI, Berettoni M, Calvani F, Catrambone F, Felicetti P, Gensini M, Terracciano R, Altamura M, Bressan A, Giuliani S, Maggi CA, Meini S, Valenti C, Quartara L. Fattori D, et al. Among authors: giuliani s. J Med Chem. 2006 Jun 15;49(12):3602-13. doi: 10.1021/jm060137l. J Med Chem. 2006. PMID: 16759102
Structure-activity relationships of 6-methyl-benzo[b]thiophene-2-carboxylic acid (1-[(S)-1-benzyl-4-[4-(tetrahydropyran-4-ylmethyl)piperazin-1-yl]butylcarbamoyl]cyclopentyl)amide, potent antagonist of the neurokinin-2 receptor.
Fattori D, Porcelloni M, D'Andrea P, Catalioto RM, Ettorre A, Giuliani S, Marastoni E, Mauro S, Meini S, Rossi C, Altamura M, Maggi CA. Fattori D, et al. Among authors: giuliani s. J Med Chem. 2010 May 27;53(10):4148-65. doi: 10.1021/jm100176s. J Med Chem. 2010. PMID: 20408549
485 results