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N,N'-Bisbenzylidenebenzene-1,4-diamines and N,N'-Bisbenzylidenenaphthalene-1,4-diamines as Sirtuin Type 2 (SIRT2) Inhibitors.
J Med Chem. 2006 Dec 28;49(26):7907-11. doi: 10.1021/jm060566j.
J Med Chem. 2006.
PMID: 17181175
Characterization of the binding properties of SIRT2 inhibitors with a N-(3-phenylpropenoyl)-glycine tryptamide backbone.
Kiviranta PH, Salo HS, Leppänen J, Rinne VM, Kyrylenko S, Kuusisto E, Suuronen T, Salminen A, Poso A, Lahtela-Kakkonen M, Wallén EA.
Kiviranta PH, et al. Among authors: salo hs.
Bioorg Med Chem. 2008 Sep 1;16(17):8054-62. doi: 10.1016/j.bmc.2008.07.059. Epub 2008 Jul 24.
Bioorg Med Chem. 2008.
PMID: 18701307
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Structure-based design of pseudopeptidic inhibitors for SIRT1 and SIRT2.
Huhtiniemi T, Salo HS, Suuronen T, Poso A, Salminen A, Leppänen J, Jarho E, Lahtela-Kakkonen M.
Huhtiniemi T, et al. Among authors: salo hs.
J Med Chem. 2011 Oct 13;54(19):6456-68. doi: 10.1021/jm200590k. Epub 2011 Sep 7.
J Med Chem. 2011.
PMID: 21895016
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Identification of novel SIRT3 inhibitor scaffolds by virtual screening.
Salo HS, Laitinen T, Poso A, Jarho E, Lahtela-Kakkonen M.
Salo HS, et al.
Bioorg Med Chem Lett. 2013 May 15;23(10):2990-5. doi: 10.1016/j.bmcl.2013.03.033. Epub 2013 Mar 16.
Bioorg Med Chem Lett. 2013.
PMID: 23562596
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Screen of pseudopeptidic inhibitors of human sirtuins 1-3: two lead compounds with antiproliferative effects in cancer cells.
Mellini P, Kokkola T, Suuronen T, Salo HS, Tolvanen L, Mai A, Lahtela-Kakkonen M, Jarho EM.
Mellini P, et al. Among authors: salo hs.
J Med Chem. 2013 Sep 12;56(17):6681-95. doi: 10.1021/jm400438k. Epub 2013 Aug 22.
J Med Chem. 2013.
PMID: 23927550
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The effect of ligand-based tautomer and protomer prediction on structure-based virtual screening.
Kalliokoski T, Salo HS, Lahtela-Kakkonen M, Poso A.
Kalliokoski T, et al. Among authors: salo hs.
J Chem Inf Model. 2009 Dec;49(12):2742-8. doi: 10.1021/ci900364w.
J Chem Inf Model. 2009.
PMID: 19928753
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Astronomy. Twisted disks.
Salo H.
Salo H.
Science. 2011 May 6;332(6030):672-3. doi: 10.1126/science.1205672.
Science. 2011.
PMID: 21551051
No abstract available.
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