Shnyder SD - Search Results

1

Synthesis of DNA-directed pyrrolidinyl and piperidinyl confined alkylating chloroalkylaminoanthraquinones: potential for development of tumor-selective N-oxides.

Pors K, Shnyder SD, Teesdale-Spittle PH, Hartley JA, Zloh M, Searcey M, Patterson LH. Pors K, et al. Among authors: shnyder sd. J Med Chem. 2006 Nov 30;49(24):7013-23. doi: 10.1021/jm0608154. J Med Chem. 2006. PMID: 17125254

2

Preliminary pharmacokinetic and bioanalytical studies of SJG-136 (NSC 694501), a sequence-selective pyrrolobenzodiazepine dimer DNA-cross-linking agent.

Wilkinson GP, Taylor JP, Shnyder S, Cooper P, Howard PW, Thurston DE, Jenkins TC, Loadman PM. Wilkinson GP, et al. Invest New Drugs. 2004 Aug;22(3):231-40. doi: 10.1023/B:DRUG.0000026249.97007.60. Invest New Drugs. 2004. PMID: 15122070

3

Synthesis of some cryptolepine analogues, assessment of their antimalarial and cytotoxic activities, and consideration of their antimalarial mode of action.

Onyeibor O, Croft SL, Dodson HI, Feiz-Haddad M, Kendrick H, Millington NJ, Parapini S, Phillips RM, Seville S, Shnyder SD, Taramelli D, Wright CW. Onyeibor O, et al. Among authors: shnyder sd. J Med Chem. 2005 Apr 7;48(7):2701-9. doi: 10.1021/jm040893w. J Med Chem. 2005. PMID: 15801861 Free article.

4

Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates.

Wells G, Martin CR, Howard PW, Sands ZA, Laughton CA, Tiberghien A, Woo CK, Masterson LA, Stephenson MJ, Hartley JA, Jenkins TC, Shnyder SD, Loadman PM, Waring MJ, Thurston DE. Wells G, et al. Among authors: shnyder sd. J Med Chem. 2006 Sep 7;49(18):5442-61. doi: 10.1021/jm051199z. J Med Chem. 2006. PMID: 16942018

5

Synthesis of cryptolepine analogues as potential bioreducible anticancer agents.

Seville S, Phillips RM, Shnyder SD, Wright CW. Seville S, et al. Among authors: shnyder sd. Bioorg Med Chem. 2007 Oct 1;15(19):6353-60. doi: 10.1016/j.bmc.2007.06.062. Epub 2007 Jul 6. Bioorg Med Chem. 2007. PMID: 17643990

6

Improved preparation and detection of cytochrome P450 isoforms using MS methods.

Sutton CW, Sutherland M, Shnyder S, Patterson LH. Sutton CW, et al. Proteomics. 2010 Jan;10(2):327-31. doi: 10.1002/pmic.200900489. Proteomics. 2010. PMID: 19902426

7

Development of a novel tumor-targeted vascular disrupting agent activated by membrane-type matrix metalloproteinases.

Atkinson JM, Falconer RA, Edwards DR, Pennington CJ, Siller CS, Shnyder SD, Bibby MC, Patterson LH, Loadman PM, Gill JH. Atkinson JM, et al. Among authors: shnyder sd. Cancer Res. 2010 Sep 1;70(17):6902-12. doi: 10.1158/0008-5472.CAN-10-1440. Epub 2010 Jul 27. Cancer Res. 2010. PMID: 20663911 Free PMC article.

8

Organometallic osmium arene complexes with potent cancer cell cytotoxicity.

Fu Y, Habtemariam A, Pizarro AM, van Rijt SH, Healey DJ, Cooper PA, Shnyder SD, Clarkson GJ, Sadler PJ. Fu Y, et al. Among authors: shnyder sd. J Med Chem. 2010 Nov 25;53(22):8192-6. doi: 10.1021/jm100560f. Epub 2010 Oct 26. J Med Chem. 2010. PMID: 20977192

9

An agarose spot chemotaxis assay for chemokine receptor antagonists.

Vinader V, Al-Saraireh Y, Wiggins HL, Rappoport JZ, Shnyder SD, Patterson LH, Afarinkia K. Vinader V, et al. Among authors: shnyder sd. J Pharmacol Toxicol Methods. 2011 Nov-Dec;64(3):213-6. doi: 10.1016/j.vascn.2011.01.004. Epub 2011 Feb 1. J Pharmacol Toxicol Methods. 2011. PMID: 21292017

10

Use of the hollow fiber assay for the evaluation of DNA damaging agents.

Veiga JP, Cooper PA, Pors K, Patterson LH, Bibby MC, Shnyder SD. Veiga JP, et al. Among authors: shnyder sd. J Pharmacol Toxicol Methods. 2011 Nov-Dec;64(3):226-32. doi: 10.1016/j.vascn.2011.04.006. Epub 2011 Apr 30. J Pharmacol Toxicol Methods. 2011. PMID: 21569858

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