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The RXR agonist bexarotene improves cholesterol homeostasis and inhibits atherosclerosis progression in a mouse model of mixed dyslipidemia.
Lalloyer F, Fiévet C, Lestavel S, Torpier G, van der Veen J, Touche V, Bultel S, Yous S, Kuipers F, Paumelle R, Fruchart JC, Staels B, Tailleux A. Lalloyer F, et al. Among authors: kuipers f. Arterioscler Thromb Vasc Biol. 2006 Dec;26(12):2731-7. doi: 10.1161/01.ATV.0000248101.93488.84. Epub 2006 Sep 28. Arterioscler Thromb Vasc Biol. 2006. PMID: 17008586
Transcriptional activation of apolipoprotein CIII expression by glucose may contribute to diabetic dyslipidemia.
Caron S, Verrijken A, Mertens I, Samanez CH, Mautino G, Haas JT, Duran-Sandoval D, Prawitt J, Francque S, Vallez E, Muhr-Tailleux A, Berard I, Kuipers F, Kuivenhoven JA, Biddinger SB, Taskinen MR, Van Gaal L, Staels B. Caron S, et al. Among authors: kuipers f. Arterioscler Thromb Vasc Biol. 2011 Mar;31(3):513-9. doi: 10.1161/ATVBAHA.110.220723. Epub 2010 Dec 23. Arterioscler Thromb Vasc Biol. 2011. PMID: 21183731
The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice.
Cariou B, van Harmelen K, Duran-Sandoval D, van Dijk TH, Grefhorst A, Abdelkarim M, Caron S, Torpier G, Fruchart JC, Gonzalez FJ, Kuipers F, Staels B. Cariou B, et al. Among authors: kuipers f. J Biol Chem. 2006 Apr 21;281(16):11039-49. doi: 10.1074/jbc.M510258200. Epub 2006 Jan 30. J Biol Chem. 2006. PMID: 16446356 Free article.
FXR-deficiency confers increased susceptibility to torpor.
Cariou B, Bouchaert E, Abdelkarim M, Dumont J, Caron S, Fruchart JC, Burcelin R, Kuipers F, Staels B. Cariou B, et al. Among authors: kuipers f. FEBS Lett. 2007 Nov 13;581(27):5191-8. doi: 10.1016/j.febslet.2007.09.064. Epub 2007 Oct 12. FEBS Lett. 2007. PMID: 17950284 Free article.
Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity.
Prawitt J, Abdelkarim M, Stroeve JH, Popescu I, Duez H, Velagapudi VR, Dumont J, Bouchaert E, van Dijk TH, Lucas A, Dorchies E, Daoudi M, Lestavel S, Gonzalez FJ, Oresic M, Cariou B, Kuipers F, Caron S, Staels B. Prawitt J, et al. Among authors: kuipers f. Diabetes. 2011 Jul;60(7):1861-71. doi: 10.2337/db11-0030. Epub 2011 May 18. Diabetes. 2011. PMID: 21593203 Free PMC article.
483 results