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p38 MAP kinase inhibitors. Part 5: discovery of an orally bio-available and highly efficacious compound based on the 7-amino-naphthyridone scaffold.
Natarajan SR, Liu L, Levorse M, Thompson JE, O'Neill EA, O'Keefe SJ, Vora KA, Cvetovich R, Chung JY, Carballo-Jane E, Visco DM. Natarajan SR, et al. Among authors: vora ka. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5468-71. doi: 10.1016/j.bmcl.2006.06.084. Epub 2006 Sep 1. Bioorg Med Chem Lett. 2006. PMID: 16945534
Profiling of hMPV F-specific antibodies isolated from human memory B cells.
Xiao X, Fridman A, Zhang L, Pristatsky P, Durr E, Minnier M, Tang A, Cox KS, Wen Z, Moore R, Tian D, Galli JD, Cosmi S, Eddins MJ, Sullivan NL, Yan X, Bett AJ, Su HP, Vora KA, Chen Z, Zhang L. Xiao X, et al. Among authors: vora ka. Nat Commun. 2022 May 10;13(1):2546. doi: 10.1038/s41467-022-30205-x. Nat Commun. 2022. PMID: 35538099 Free PMC article.
A potent broadly neutralizing human RSV antibody targets conserved site IV of the fusion glycoprotein.
Tang A, Chen Z, Cox KS, Su HP, Callahan C, Fridman A, Zhang L, Patel SB, Cejas PJ, Swoyer R, Touch S, Citron MP, Govindarajan D, Luo B, Eddins M, Reid JC, Soisson SM, Galli J, Wang D, Wen Z, Heidecker GJ, Casimiro DR, DiStefano DJ, Vora KA. Tang A, et al. Among authors: vora ka. Nat Commun. 2019 Sep 12;10(1):4153. doi: 10.1038/s41467-019-12137-1. Nat Commun. 2019. PMID: 31515478 Free PMC article.
Development of a microneutralization assay for HSV-2.
Horton MS, Minnier M, Cosmi S, Cox K, Galli J, Peters J, Sullivan N, Squadroni B, Tang A, Fridman A, Wang D, Chen Z, Vora KA. Horton MS, et al. Among authors: vora ka. J Virol Methods. 2021 Nov;297:114268. doi: 10.1016/j.jviromet.2021.114268. Epub 2021 Aug 24. J Virol Methods. 2021. PMID: 34437874
62 results