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Elevated cortical zinc in Alzheimer disease.
Religa D, Strozyk D, Cherny RA, Volitakis I, Haroutunian V, Winblad B, Naslund J, Bush AI. Religa D, et al. Among authors: volitakis i. Neurology. 2006 Jul 11;67(1):69-75. doi: 10.1212/01.wnl.0000223644.08653.b5. Neurology. 2006. PMID: 16832080
Metal-protein attenuation with iodochlorhydroxyquin (clioquinol) targeting Abeta amyloid deposition and toxicity in Alzheimer disease: a pilot phase 2 clinical trial.
Ritchie CW, Bush AI, Mackinnon A, Macfarlane S, Mastwyk M, MacGregor L, Kiers L, Cherny R, Li QX, Tammer A, Carrington D, Mavros C, Volitakis I, Xilinas M, Ames D, Davis S, Beyreuther K, Tanzi RE, Masters CL. Ritchie CW, et al. Among authors: volitakis i. Arch Neurol. 2003 Dec;60(12):1685-91. doi: 10.1001/archneur.60.12.1685. Arch Neurol. 2003. PMID: 14676042 Clinical Trial.
Zinc and copper modulate Alzheimer Abeta levels in human cerebrospinal fluid.
Strozyk D, Launer LJ, Adlard PA, Cherny RA, Tsatsanis A, Volitakis I, Blennow K, Petrovitch H, White LR, Bush AI. Strozyk D, et al. Among authors: volitakis i. Neurobiol Aging. 2009 Jul;30(7):1069-77. doi: 10.1016/j.neurobiolaging.2007.10.012. Epub 2007 Dec 18. Neurobiol Aging. 2009. PMID: 18068270 Free PMC article.
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits.
Curtain CC, Ali F, Volitakis I, Cherny RA, Norton RS, Beyreuther K, Barrow CJ, Masters CL, Bush AI, Barnham KJ. Curtain CC, et al. Among authors: volitakis i. J Biol Chem. 2001 Jun 8;276(23):20466-73. doi: 10.1074/jbc.M100175200. Epub 2001 Mar 27. J Biol Chem. 2001. PMID: 11274207 Free article.
93 results