Majumdar MK - Search Results

1

Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.

LaVallie ER, Chockalingam PS, Collins-Racie LA, Freeman BA, Keohan CC, Leitges M, Dorner AJ, Morris EA, Majumdar MK, Arai M. LaVallie ER, et al. Among authors: majumdar mk. J Biol Chem. 2006 Aug 25;281(34):24124-37. doi: 10.1074/jbc.M601905200. Epub 2006 Jun 23. J Biol Chem. 2006. PMID: 16798739 Free article.

2

Immortalized mouse articular cartilage cell lines retain chondrocyte phenotype and respond to both anabolic factor BMP-2 and pro-inflammatory factor IL-1.

Majumdar MK, Chockalingam PS, Bhat RA, Sheldon R, Keohan C, Blanchet T, Glasson S, Morris EA. Majumdar MK, et al. J Cell Physiol. 2008 Apr;215(1):68-76. doi: 10.1002/jcp.21282. J Cell Physiol. 2008. PMID: 17960567

3

Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes.

Chockalingam PS, Varadarajan U, Sheldon R, Fortier E, LaVallie ER, Morris EA, Yaworsky PJ, Majumdar MK. Chockalingam PS, et al. Among authors: majumdar mk. Arthritis Rheum. 2007 Dec;56(12):4074-83. doi: 10.1002/art.23043. Arthritis Rheum. 2007. PMID: 18050214 Free article.

4

Synthesis and biological evaluation of biphenylsulfonamide carboxylate aggrecanase-1 inhibitors.

Xiang JS, Hu Y, Rush TS, Thomason JR, Ipek M, Sum PE, Abrous L, Sabatini JJ, Georgiadis K, Reifenberg E, Majumdar M, Morris EA, Tam S. Xiang JS, et al. Bioorg Med Chem Lett. 2006 Jan 15;16(2):311-6. doi: 10.1016/j.bmcl.2005.10.001. Epub 2005 Nov 3. Bioorg Med Chem Lett. 2006. PMID: 16275085

5

Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice.

Glasson SS, Askew R, Sheppard B, Carito BA, Blanchet T, Ma HL, Flannery CR, Kanki K, Wang E, Peluso D, Yang Z, Majumdar MK, Morris EA. Glasson SS, et al. Among authors: majumdar mk. Arthritis Rheum. 2004 Aug;50(8):2547-58. doi: 10.1002/art.20558. Arthritis Rheum. 2004. PMID: 15334469 Free article.

6

Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype.

Majumdar MK, Chockalingam PS, Bhat RA, Sheldon R, Keohan C, Blanchet T, Glasson S, Morris EA. Majumdar MK, et al. J Cell Physiol. 2006 Nov;209(2):551-9. doi: 10.1002/jcp.20775. J Cell Physiol. 2006. PMID: 16883582

7

Double-knockout of ADAMTS-4 and ADAMTS-5 in mice results in physiologically normal animals and prevents the progression of osteoarthritis.

Majumdar MK, Askew R, Schelling S, Stedman N, Blanchet T, Hopkins B, Morris EA, Glasson SS. Majumdar MK, et al. Arthritis Rheum. 2007 Nov;56(11):3670-4. doi: 10.1002/art.23027. Arthritis Rheum. 2007. PMID: 17968948 Free article.

8

Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors.

Hopper DW, Vera MD, How D, Sabatini J, Xiang JS, Ipek M, Thomason J, Hu Y, Feyfant E, Wang Q, Georgiadis KE, Reifenberg E, Sheldon RT, Keohan CC, Majumdar MK, Morris EA, Skotnicki J, Sum PE. Hopper DW, et al. Among authors: majumdar mk. Bioorg Med Chem Lett. 2009 May 1;19(9):2487-91. doi: 10.1016/j.bmcl.2009.03.056. Epub 2009 Mar 18. Bioorg Med Chem Lett. 2009. PMID: 19329309

9

BMP-2 and BMP-9 promotes chondrogenic differentiation of human multipotential mesenchymal cells and overcomes the inhibitory effect of IL-1.

Majumdar MK, Wang E, Morris EA. Majumdar MK, et al. J Cell Physiol. 2001 Dec;189(3):275-84. doi: 10.1002/jcp.10025. J Cell Physiol. 2001. PMID: 11748585

10

Global analysis of nuclear receptor expression and dysregulation in human osteoarthritic articular cartilage: reduced LXR signaling contributes to catabolic metabolism typical of osteoarthritis.

Collins-Racie LA, Yang Z, Arai M, Li N, Majumdar MK, Nagpal S, Mounts WM, Dorner AJ, Morris E, LaVallie ER. Collins-Racie LA, et al. Among authors: majumdar mk. Osteoarthritis Cartilage. 2009 Jul;17(7):832-42. doi: 10.1016/j.joca.2008.12.011. Epub 2009 Jan 19. Osteoarthritis Cartilage. 2009. PMID: 19217805 Free article.

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