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Protein kinase Czeta is up-regulated in osteoarthritic cartilage and is required for activation of NF-kappaB by tumor necrosis factor and interleukin-1 in articular chondrocytes.
J Biol Chem. 2006 Aug 25;281(34):24124-37. doi: 10.1074/jbc.M601905200. Epub 2006 Jun 23.
J Biol Chem. 2006.
PMID: 16798739
Free article.
Immortalized mouse articular cartilage cell lines retain chondrocyte phenotype and respond to both anabolic factor BMP-2 and pro-inflammatory factor IL-1.
Majumdar MK, Chockalingam PS, Bhat RA, Sheldon R, Keohan C, Blanchet T, Glasson S, Morris EA.
Majumdar MK, et al.
J Cell Physiol. 2008 Apr;215(1):68-76. doi: 10.1002/jcp.21282.
J Cell Physiol. 2008.
PMID: 17960567
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Immortalized cell lines from mouse xiphisternum preserve chondrocyte phenotype.
Majumdar MK, Chockalingam PS, Bhat RA, Sheldon R, Keohan C, Blanchet T, Glasson S, Morris EA.
Majumdar MK, et al.
J Cell Physiol. 2006 Nov;209(2):551-9. doi: 10.1002/jcp.20775.
J Cell Physiol. 2006.
PMID: 16883582
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Synthesis and biological evaluation of ((4-keto)-phenoxy)methyl biphenyl-4-sulfonamides: a class of potent aggrecanase-1 inhibitors.
Hopper DW, Vera MD, How D, Sabatini J, Xiang JS, Ipek M, Thomason J, Hu Y, Feyfant E, Wang Q, Georgiadis KE, Reifenberg E, Sheldon RT, Keohan CC, Majumdar MK, Morris EA, Skotnicki J, Sum PE.
Hopper DW, et al. Among authors: keohan cc.
Bioorg Med Chem Lett. 2009 May 1;19(9):2487-91. doi: 10.1016/j.bmcl.2009.03.056. Epub 2009 Mar 18.
Bioorg Med Chem Lett. 2009.
PMID: 19329309
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