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Synthesis and evaluation of 5,5-diphenylimidazolones as potent human neuropeptide Y5 receptor antagonists.
Bioorg Med Chem. 2006 Aug 15;14(16):5517-26. doi: 10.1016/j.bmc.2006.04.042. Epub 2006 May 11.
Bioorg Med Chem. 2006.
PMID: 16697206
Dihydropyridine neuropeptide Y Y(1) receptor antagonists.
Poindexter GS, Bruce MA, LeBoulluec KL, Monkovic I, Martin SW, Parker EM, Iben LG, McGovern RT, Ortiz AA, Stanley JA, Mattson GK, Kozlowski M, Arcuri M, Antal-Zimanyi I.
Poindexter GS, et al. Among authors: mcgovern rt.
Bioorg Med Chem Lett. 2002 Feb 11;12(3):379-82. doi: 10.1016/s0960-894x(01)00761-2.
Bioorg Med Chem Lett. 2002.
PMID: 11814801
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Dihydropyridine neuropeptide Y Y1 receptor antagonists 2. bioisosteric urea replacements.
Poindexter GS, Bruce MA, Breitenbucher JG, Higgins MA, Sit SY, Romine JL, Martin SW, Ward SA, McGovern RT, Clarke W, Russell J, Antal-Zimanyi I.
Poindexter GS, et al. Among authors: mcgovern rt.
Bioorg Med Chem. 2004 Jan 15;12(2):507-21. doi: 10.1016/j.bmc.2003.10.016.
Bioorg Med Chem. 2004.
PMID: 14723969
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Pharmacological characterization and appetite suppressive properties of BMS-193885, a novel and selective neuropeptide Y(1) receptor antagonist.
Antal-Zimanyi I, Bruce MA, Leboulluec KL, Iben LG, Mattson GK, McGovern RT, Hogan JB, Leahy CL, Flowers SC, Stanley JA, Ortiz AA, Poindexter GS.
Antal-Zimanyi I, et al. Among authors: mcgovern rt.
Eur J Pharmacol. 2008 Aug 20;590(1-3):224-32. doi: 10.1016/j.ejphar.2008.06.032. Epub 2008 Jun 12.
Eur J Pharmacol. 2008.
PMID: 18573246
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Development of a presynaptic 5-HT1A antagonist.
Mattson RJ, Catt JD, Sloan CP, Gao Q, Carter RB, Gentile A, Mahle CD, Matos FF, McGovern R, VanderMaelen CP, Yocca FD.
Mattson RJ, et al.
Bioorg Med Chem Lett. 2003 Jan 20;13(2):285-8. doi: 10.1016/s0960-894x(02)00879-x.
Bioorg Med Chem Lett. 2003.
PMID: 12482441
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Molecular characterization, pharmacological properties and chromosomal localization of the human GALR2 galanin receptor.
Fathi Z, Battaglino PM, Iben LG, Li H, Baker E, Zhang D, McGovern R, Mahle CD, Sutherland GR, Iismaa TP, Dickinson KE, Zimanyi IA.
Fathi Z, et al.
Brain Res Mol Brain Res. 1998 Jul 15;58(1-2):156-69. doi: 10.1016/s0169-328x(98)00116-8.
Brain Res Mol Brain Res. 1998.
PMID: 9685625
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