Takami M - Search Results

1

Equimolar production of amyloid beta-protein and amyloid precursor protein intracellular domain from beta-carboxyl-terminal fragment by gamma-secretase.

Kakuda N, Funamoto S, Yagishita S, Takami M, Osawa S, Dohmae N, Ihara Y. Kakuda N, et al. Among authors: takami m. J Biol Chem. 2006 May 26;281(21):14776-86. doi: 10.1074/jbc.M513453200. Epub 2006 Apr 4. J Biol Chem. 2006. PMID: 16595682 Free article.

2

gamma-Secretase: successive tripeptide and tetrapeptide release from the transmembrane domain of beta-carboxyl terminal fragment.

Takami M, Nagashima Y, Sano Y, Ishihara S, Morishima-Kawashima M, Funamoto S, Ihara Y. Takami M, et al. J Neurosci. 2009 Oct 14;29(41):13042-52. doi: 10.1523/JNEUROSCI.2362-09.2009. J Neurosci. 2009. PMID: 19828817 Free PMC article.

3

γ-Secretase associated with lipid rafts: multiple interactive pathways in the stepwise processing of β-carboxyl-terminal fragment.

Matsumura N, Takami M, Okochi M, Wada-Kakuda S, Fujiwara H, Tagami S, Funamoto S, Ihara Y, Morishima-Kawashima M. Matsumura N, et al. Among authors: takami m. J Biol Chem. 2014 Feb 21;289(8):5109-21. doi: 10.1074/jbc.M113.510131. Epub 2013 Dec 28. J Biol Chem. 2014. PMID: 24375443 Free PMC article.

4

γ-Secretase-Dependent Proteolysis of Transmembrane Domain of Amyloid Precursor Protein: Successive Tri- and Tetrapeptide Release in Amyloid β-Protein Production.

Takami M, Funamoto S. Takami M, et al. Int J Alzheimers Dis. 2012;2012:591392. doi: 10.1155/2012/591392. Epub 2012 Dec 31. Int J Alzheimers Dis. 2012. PMID: 23346458 Free PMC article.

5

Switched Aβ43 generation in familial Alzheimer's disease with presenilin 1 mutation.

Kakuda N, Takami M, Okochi M, Kasuga K, Ihara Y, Ikeuchi T. Kakuda N, et al. Among authors: takami m. Transl Psychiatry. 2021 Nov 3;11(1):558. doi: 10.1038/s41398-021-01684-1. Transl Psychiatry. 2021. PMID: 34728605 Free PMC article.

6

Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease.

Kakuda N, Shoji M, Arai H, Furukawa K, Ikeuchi T, Akazawa K, Takami M, Hatsuta H, Murayama S, Hashimoto Y, Miyajima M, Arai H, Nagashima Y, Yamaguchi H, Kuwano R, Nagaike K, Ihara Y; Japanese Alzheimer's Disease Neuroimaging Initiative. Kakuda N, et al. Among authors: takami m. EMBO Mol Med. 2012 Apr;4(4):344-52. doi: 10.1002/emmm.201200214. Epub 2012 Feb 21. EMBO Mol Med. 2012. PMID: 22354516 Free PMC article.

7

γ-secretase modulators and presenilin 1 mutants act differently on presenilin/γ-secretase function to cleave Aβ42 and Aβ43.

Okochi M, Tagami S, Yanagida K, Takami M, Kodama TS, Mori K, Nakayama T, Ihara Y, Takeda M. Okochi M, et al. Among authors: takami m. Cell Rep. 2013 Jan 31;3(1):42-51. doi: 10.1016/j.celrep.2012.11.028. Epub 2013 Jan 3. Cell Rep. 2013. PMID: 23291095 Free article.

8

Semagacestat Is a Pseudo-Inhibitor of γ-Secretase.

Tagami S, Yanagida K, Kodama TS, Takami M, Mizuta N, Oyama H, Nishitomi K, Chiu YW, Okamoto T, Ikeuchi T, Sakaguchi G, Kudo T, Matsuura Y, Fukumori A, Takeda M, Ihara Y, Okochi M. Tagami S, et al. Among authors: takami m. Cell Rep. 2017 Oct 3;21(1):259-273. doi: 10.1016/j.celrep.2017.09.032. Cell Rep. 2017. PMID: 28978478 Free article.

9

Identification of Small Peptides in Human Cerebrospinal Fluid upon Amyloid-β Degradation.

Mizuta N, Yanagida K, Kodama T, Tomonaga T, Takami M, Oyama H, Kudo T, Ikeda M, Takeda M, Tagami S, Okochi M. Mizuta N, et al. Among authors: takami m. Neurodegener Dis. 2017;17(2-3):103-109. doi: 10.1159/000453358. Epub 2017 Jan 20. Neurodegener Dis. 2017. PMID: 28103595

10

Skeletal muscle metabolic dysfunction with circulating carboxymethyl-lysine in dietary food additive-induced leaky gut.

Kodani H, Aoi W, Hirata M, Takami M, Kobayashi Y, Kuwahata M. Kodani H, et al. Among authors: takami m. FASEB J. 2024 Jun 15;38(11):e23715. doi: 10.1096/fj.202302473R. FASEB J. 2024. PMID: 38837260

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