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Evaluation of hydroxyimine as cytochrome P450-selective prodrug structure.
J Med Chem. 2006 Feb 9;49(3):1207-11. doi: 10.1021/jm0510124.
J Med Chem. 2006.
PMID: 16451086
Novel cyclic phosphate prodrug approach for cytochrome P450-activated drugs containing an alcohol functionality.
Huttunen KM, Mähönen N, Leppänen J, Vepsäläinen J, Juvonen RO, Raunio H, Kumpulainen H, Järvinen T, Rautio J.
Huttunen KM, et al. Among authors: mahonen n.
Pharm Res. 2007 Apr;24(4):679-87. doi: 10.1007/s11095-006-9187-y. Epub 2007 Feb 15.
Pharm Res. 2007.
PMID: 17372695
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Cytochrome P450-activated prodrugs: targeted drug delivery.
Huttunen KM, Mähönen N, Raunio H, Rautio J.
Huttunen KM, et al. Among authors: mahonen n.
Curr Med Chem. 2008;15(23):2346-65. doi: 10.2174/092986708785909120.
Curr Med Chem. 2008.
PMID: 18855665
Review.
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Predictive three-dimensional quantitative structure-activity relationship of cytochrome P450 1A2 inhibitors.
Korhonen LE, Rahnasto M, Mähönen NJ, Wittekindt C, Poso A, Juvonen RO, Raunio H.
Korhonen LE, et al. Among authors: mahonen nj.
J Med Chem. 2005 Jun 2;48(11):3808-15. doi: 10.1021/jm0489713.
J Med Chem. 2005.
PMID: 15916432
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