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Oral imatinib treatment reduces early fibrogenesis but does not prevent progression in the long term.
J Hepatol. 2006 Jan;44(1):167-75. doi: 10.1016/j.jhep.2005.06.015. Epub 2005 Jul 12.
J Hepatol. 2006.
PMID: 16168515
Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis.
Neef M, Ledermann M, Saegesser H, Schneider V, Reichen J.
Neef M, et al. Among authors: saegesser h.
J Hepatol. 2006 Dec;45(6):786-96. doi: 10.1016/j.jhep.2006.07.030. Epub 2006 Sep 22.
J Hepatol. 2006.
PMID: 17050028
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Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis.
Patsenker E, Schneider V, Ledermann M, Saegesser H, Dorn C, Hellerbrand C, Stickel F.
Patsenker E, et al. Among authors: saegesser h.
J Hepatol. 2011 Aug;55(2):388-98. doi: 10.1016/j.jhep.2010.10.044. Epub 2010 Dec 17.
J Hepatol. 2011.
PMID: 21168455
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Endothelial nitric oxide synthase is not essential for the development of fibrosis and portal hypertension in bile duct ligated mice.
Koshy A, De Gottardi A, Ledermann M, Saegesser H, Shaw SG, Zimmermann A, Reichen J.
Koshy A, et al. Among authors: saegesser h.
Liver Int. 2005 Oct;25(5):1044-52. doi: 10.1111/j.1478-3231.2005.01146.x.
Liver Int. 2005.
PMID: 16162165
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