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The Dual Targeting of FcRn and FcγRs via Monomeric Fc Fragments Results in Strong Inhibition of IgG-Dependent Autoimmune Pathologies.
Monnet C, Jacque E, de Romeuf C, Fontayne A, Abache T, Fournier N, Dupont G, Derache D, Engrand A, Bauduin A, Terrier A, Seifert A, Beghin C, Longue A, Masiello N, Danino L, Nogre M, Raia A, Dhainaut F, Fauconnier L, Togbe D, Reitinger C, Nimmerjahn F, Stevens W, Chtourou S, Mondon P. Monnet C, et al. Among authors: dhainaut f. Front Immunol. 2021 Aug 26;12:728322. doi: 10.3389/fimmu.2021.728322. eCollection 2021. Front Immunol. 2021. PMID: 34512662 Free PMC article.
A human anti-D monoclonal antibody selected for enhanced FcgammaRIII engagement clears RhD+ autologous red cells in human volunteers as efficiently as polyclonal anti-D antibodies.
Beliard R, Waegemans T, Notelet D, Massad L, Dhainaut F, Romeuf Cd, Guemas E, Haazen W, Bourel D, Teillaud JL, Prost JF. Beliard R, et al. Among authors: dhainaut f. Br J Haematol. 2008 Apr;141(1):109-19. doi: 10.1111/j.1365-2141.2008.06985.x. Epub 2008 Feb 12. Br J Haematol. 2008. PMID: 18279459 Free article. Clinical Trial.
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