Nishino T - Search Results

1

Redox system expression in the motor neurons in amyotrophic lateral sclerosis (ALS): immunohistochemical studies on sporadic ALS, superoxide dismutase 1 (SOD1)-mutated familial ALS, and SOD1-mutated ALS animal models.

Kato S, Kato M, Abe Y, Matsumura T, Nishino T, Aoki M, Itoyama Y, Asayama K, Awaya A, Hirano A, Ohama E. Kato S, et al. Among authors: nishino t. Acta Neuropathol. 2005 Aug;110(2):101-12. doi: 10.1007/s00401-005-1019-3. Epub 2005 Jun 28. Acta Neuropathol. 2005. PMID: 15983830

2

New Strategy That Delays Progression of Amyotrophic Lateral Sclerosis in G1H-G93A Transgenic Mice: Oral Administration of Xanthine Oxidoreductase Inhibitors That Are Not Substrates for the Purine Salvage Pathway.

Kato S, Kato M, Kusano T, Nishino T. Kato S, et al. Among authors: nishino t. J Neuropathol Exp Neurol. 2016 Dec 1;75(12):1124-1144. doi: 10.1093/jnen/nlw088. J Neuropathol Exp Neurol. 2016. PMID: 27815397

3

Dimer-oligomer interconversion of wild-type and mutant rat 2-Cys peroxiredoxin: disulfide formation at dimer-dimer interfaces is not essential for decamerization.

Matsumura T, Okamoto K, Iwahara SI, Hori H, Takahashi Y, Nishino T, Abe Y. Matsumura T, et al. Among authors: nishino t. J Biol Chem. 2008 Jan 4;283(1):284-293. doi: 10.1074/jbc.M705753200. Epub 2007 Nov 1. J Biol Chem. 2008. PMID: 17974571 Free article.

The C83S mutant was predominantly dimeric, in agreement with a previous crystallographic analysis (Hirotsu, S., Abe, Y., Okada, K., Nagahara, N., Hori, H., Nishino, T., and Hakoshima, T. (1999) Proc. Natl. Acad. Sci. U. S. ...

The C83S mutant was predominantly dimeric, in agreement with a previous crystallographic analysis (Hirotsu, S., Abe, Y., Okada, K., Nagahara …

4

Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate.

Yamaguchi Y, Matsumura T, Ichida K, Okamoto K, Nishino T. Yamaguchi Y, et al. Among authors: nishino t. J Biochem. 2007 Apr;141(4):513-24. doi: 10.1093/jb/mvm053. Epub 2007 Feb 14. J Biochem. 2007. PMID: 17301077

5

Mechanism of the conversion of xanthine dehydrogenase to xanthine oxidase: identification of the two cysteine disulfide bonds and crystal structure of a non-convertible rat liver xanthine dehydrogenase mutant.

Nishino T, Okamoto K, Kawaguchi Y, Hori H, Matsumura T, Eger BT, Pai EF, Nishino T. Nishino T, et al. J Biol Chem. 2005 Jul 1;280(26):24888-94. doi: 10.1074/jbc.M501830200. Epub 2005 May 4. J Biol Chem. 2005. PMID: 15878860 Free article.

6

Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase.

Asai R, Nishino T, Matsumura T, Okamoto K, Igarashi K, Pai EF, Nishino T. Asai R, et al. Among authors: nishino t. J Biochem. 2007 Apr;141(4):525-34. doi: 10.1093/jb/mvm054. Epub 2007 Feb 14. J Biochem. 2007. PMID: 17301076

7

Expression of cochlin mRNA splice variants in the inner ear.

Sekine K, Ikezono T, Matsumura T, Shindo S, Watanabe A, Li L, Pawankar R, Nishino T, Yagi T. Sekine K, et al. Among authors: nishino t. Audiol Neurootol. 2010;15(2):88-96. doi: 10.1159/000231634. Epub 2009 Aug 4. Audiol Neurootol. 2010. PMID: 19657184

8

Unique amino acids cluster for switching from the dehydrogenase to oxidase form of xanthine oxidoreductase.

Kuwabara Y, Nishino T, Okamoto K, Matsumura T, Eger BT, Pai EF, Nishino T. Kuwabara Y, et al. Among authors: nishino t. Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8170-5. doi: 10.1073/pnas.1431485100. Epub 2003 Jun 19. Proc Natl Acad Sci U S A. 2003. PMID: 12817083 Free PMC article.

9

The C-terminal peptide plays a role in the formation of an intermediate form during the transition between xanthine dehydrogenase and xanthine oxidase.

Nishino T, Okamoto K, Kawaguchi Y, Matsumura T, Eger BT, Pai EF, Nishino T. Nishino T, et al. FEBS J. 2015 Aug;282(16):3075-90. doi: 10.1111/febs.13277. Epub 2015 Apr 13. FEBS J. 2015. PMID: 25817260 Free PMC article.

10

Targeted knock-in mice expressing the oxidase-fixed form of xanthine oxidoreductase favor tumor growth.

Kusano T, Ehirchiou D, Matsumura T, Chobaz V, Nasi S, Castelblanco M, So A, Lavanchy C, Acha-Orbea H, Nishino T, Okamoto K, Busso N. Kusano T, et al. Among authors: nishino t. Nat Commun. 2019 Oct 28;10(1):4904. doi: 10.1038/s41467-019-12565-z. Nat Commun. 2019. PMID: 31659168 Free PMC article.

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