Lochhead J - Search Results

1

Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

Sparks DL, Sabbagh MN, Connor DJ, Lopez J, Launer LJ, Browne P, Wasser D, Johnson-Traver S, Lochhead J, Ziolwolski C. Sparks DL, et al. Among authors: lochhead j. Arch Neurol. 2005 May;62(5):753-7. doi: 10.1001/archneur.62.5.753. Arch Neurol. 2005. PMID: 15883262 Clinical Trial.

2

Atorvastatin therapy lowers circulating cholesterol but not free radical activity in advance of identifiable clinical benefit in the treatment of mild-to-moderate AD.

Sparks DL, Sabbagh MN, Connor DJ, Lopez J, Launer LJ, Petanceska S, Browne P, Wassar D, Johnson-Traver S, Lochhead J, Ziolkowski C. Sparks DL, et al. Among authors: lochhead j. Curr Alzheimer Res. 2005 Jul;2(3):343-53. doi: 10.2174/1567205054367900. Curr Alzheimer Res. 2005. PMID: 15974900 Clinical Trial.

3

Cholesterol, copper and Abeta in controls, MCI, AD and the AD cholesterol-lowering treatment trial (ADCLT).

Sparks DL, Petanceska S, Sabbagh M, Connor D, Soares H, Adler C, Lopez J, Ziolkowski C, Lochhead J, Browne P. Sparks DL, et al. Among authors: lochhead j. Curr Alzheimer Res. 2005 Dec;2(5):527-39. doi: 10.2174/156720505774932296. Curr Alzheimer Res. 2005. PMID: 16375656 Clinical Trial.

4

Water quality has a pronounced effect on cholesterol-induced accumulation of Alzheimer amyloid beta (Abeta) in rabbit brain.

Sparks DL, Lochhead J, Horstman D, Wagoner T, Martin T. Sparks DL, et al. Among authors: lochhead j. J Alzheimers Dis. 2002 Dec;4(6):523-9. doi: 10.3233/jad-2002-4609. J Alzheimers Dis. 2002. PMID: 12515903

5

Cholesterol modifies classical conditioning of the rabbit (Oryctolagus cuniculus) nictitating membrane response.

Schreurs BG, Smith-Bell CA, Lochhead J, Sparks DL. Schreurs BG, et al. Among authors: lochhead j. Behav Neurosci. 2003 Dec;117(6):1220-32. doi: 10.1037/0735-7044.117.6.1220. Behav Neurosci. 2003. PMID: 14674842

6

Distribution of insulin in trigeminal nerve and brain after intranasal administration.

Lochhead JJ, Kellohen KL, Ronaldson PT, Davis TP. Lochhead JJ, et al. Sci Rep. 2019 Feb 22;9(1):2621. doi: 10.1038/s41598-019-39191-5. Sci Rep. 2019. PMID: 30796294 Free PMC article.

7

Oxidative stress increases blood-brain barrier permeability and induces alterations in occludin during hypoxia-reoxygenation.

Lochhead JJ, McCaffrey G, Quigley CE, Finch J, DeMarco KM, Nametz N, Davis TP. Lochhead JJ, et al. J Cereb Blood Flow Metab. 2010 Sep;30(9):1625-36. doi: 10.1038/jcbfm.2010.29. Epub 2010 Mar 17. J Cereb Blood Flow Metab. 2010. PMID: 20234382 Free PMC article.

8

Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress.

McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP. McCaffrey G, et al. Among authors: lochhead jj. J Neurochem. 2009 Jul;110(1):58-71. doi: 10.1111/j.1471-4159.2009.06113.x. Epub 2009 May 15. J Neurochem. 2009. PMID: 19457074 Free PMC article.

9

Perivascular and Perineural Pathways Involved in Brain Delivery and Distribution of Drugs after Intranasal Administration.

Lochhead JJ, Davis TP. Lochhead JJ, et al. Pharmaceutics. 2019 Nov 12;11(11):598. doi: 10.3390/pharmaceutics11110598. Pharmaceutics. 2019. PMID: 31726721 Free PMC article. Review.

10

High-Dose Acetaminophen Alters the Integrity of the Blood-Brain Barrier and Leads to Increased CNS Uptake of Codeine in Rats.

Yang J, Betterton RD, Williams EI, Stanton JA, Reddell ES, Ogbonnaya CE, Dorn E, Davis TP, Lochhead JJ, Ronaldson PT. Yang J, et al. Among authors: lochhead jj. Pharmaceutics. 2022 Apr 27;14(5):949. doi: 10.3390/pharmaceutics14050949. Pharmaceutics. 2022. PMID: 35631535 Free PMC article.

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