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Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Cancer Cell. 2005 Apr;7(4):387-97. doi: 10.1016/j.ccr.2005.03.023.
Cancer Cell. 2005.
PMID: 15837627
Free article.
FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia.
Lee BH, Tothova Z, Levine RL, Anderson K, Buza-Vidas N, Cullen DE, McDowell EP, Adelsperger J, Fröhling S, Huntly BJ, Beran M, Jacobsen SE, Gilliland DG.
Lee BH, et al. Among authors: adelsperger j.
Cancer Cell. 2007 Oct;12(4):367-80. doi: 10.1016/j.ccr.2007.08.031.
Cancer Cell. 2007.
PMID: 17936561
Free PMC article.
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Activation mutations of human c-KIT resistant to imatinib mesylate are sensitive to the tyrosine kinase inhibitor PKC412.
Growney JD, Clark JJ, Adelsperger J, Stone R, Fabbro D, Griffin JD, Gilliland DG.
Growney JD, et al. Among authors: adelsperger j.
Blood. 2005 Jul 15;106(2):721-4. doi: 10.1182/blood-2004-12-4617. Epub 2005 Mar 24.
Blood. 2005.
PMID: 15790786
Free PMC article.
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The small molecule tyrosine kinase inhibitor AMN107 inhibits TEL-PDGFRbeta and FIP1L1-PDGFRalpha in vitro and in vivo.
Stover EH, Chen J, Lee BH, Cools J, McDowell E, Adelsperger J, Cullen D, Coburn A, Moore SA, Okabe R, Fabbro D, Manley PW, Griffin JD, Gilliland DG.
Stover EH, et al. Among authors: adelsperger j.
Blood. 2005 Nov 1;106(9):3206-13. doi: 10.1182/blood-2005-05-1932. Epub 2005 Jul 19.
Blood. 2005.
PMID: 16030188
Free PMC article.
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FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies.
Chen J, Lee BH, Williams IR, Kutok JL, Mitsiades CS, Duclos N, Cohen S, Adelsperger J, Okabe R, Coburn A, Moore S, Huntly BJ, Fabbro D, Anderson KC, Griffin JD, Gilliland DG.
Chen J, et al. Among authors: adelsperger j.
Oncogene. 2005 Dec 15;24(56):8259-67. doi: 10.1038/sj.onc.1208989.
Oncogene. 2005.
PMID: 16091734
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PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder.
Chen J, Deangelo DJ, Kutok JL, Williams IR, Lee BH, Wadleigh M, Duclos N, Cohen S, Adelsperger J, Okabe R, Coburn A, Galinsky I, Huntly B, Cohen PS, Meyer T, Fabbro D, Roesel J, Banerji L, Griffin JD, Xiao S, Fletcher JA, Stone RM, Gilliland DG.
Chen J, et al. Among authors: adelsperger j.
Proc Natl Acad Sci U S A. 2004 Oct 5;101(40):14479-84. doi: 10.1073/pnas.0404438101. Epub 2004 Sep 24.
Proc Natl Acad Sci U S A. 2004.
PMID: 15448205
Free PMC article.
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Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype.
Growney JD, Shigematsu H, Li Z, Lee BH, Adelsperger J, Rowan R, Curley DP, Kutok JL, Akashi K, Williams IR, Speck NA, Gilliland DG.
Growney JD, et al. Among authors: adelsperger j.
Blood. 2005 Jul 15;106(2):494-504. doi: 10.1182/blood-2004-08-3280. Epub 2005 Mar 22.
Blood. 2005.
PMID: 15784726
Free PMC article.
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Early soft tissue pathosis associated with impacted third molars without pericoronal radiolucency.
Adelsperger J, Campbell JH, Coates DB, Summerlin DJ, Tomich CE.
Adelsperger J, et al.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000 Apr;89(4):402-6. doi: 10.1016/s1079-2104(00)70119-3.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2000.
PMID: 10760721
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