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A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis.
De Gendt K, Swinnen JV, Saunders PT, Schoonjans L, Dewerchin M, Devos A, Tan K, Atanassova N, Claessens F, Lécureuil C, Heyns W, Carmeliet P, Guillou F, Sharpe RM, Verhoeven G. De Gendt K, et al. Among authors: verhoeven g. Proc Natl Acad Sci U S A. 2004 Feb 3;101(5):1327-32. doi: 10.1073/pnas.0308114100. Epub 2004 Jan 26. Proc Natl Acad Sci U S A. 2004. PMID: 14745012 Free PMC article.
Development and function of the adult generation of Leydig cells in mice with Sertoli cell-selective or total ablation of the androgen receptor.
De Gendt K, Atanassova N, Tan KA, de França LR, Parreira GG, McKinnell C, Sharpe RM, Saunders PT, Mason JI, Hartung S, Ivell R, Denolet E, Verhoeven G. De Gendt K, et al. Among authors: verhoeven g. Endocrinology. 2005 Sep;146(9):4117-26. doi: 10.1210/en.2005-0300. Epub 2005 May 26. Endocrinology. 2005. PMID: 15919750
Role of androgens in fetal testis development and dysgenesis.
Scott HM, Hutchison GR, Mahood IK, Hallmark N, Welsh M, De Gendt K, Verhoeven G, O'Shaughnessy P, Sharpe RM. Scott HM, et al. Among authors: verhoeven g. Endocrinology. 2007 May;148(5):2027-36. doi: 10.1210/en.2006-1622. Epub 2007 Feb 8. Endocrinology. 2007. PMID: 17289843
Loss of androgen receptor binding to selective androgen response elements causes a reproductive phenotype in a knockin mouse model.
Schauwaers K, De Gendt K, Saunders PT, Atanassova N, Haelens A, Callewaert L, Moehren U, Swinnen JV, Verhoeven G, Verrijdt G, Claessens F. Schauwaers K, et al. Among authors: verhoeven g. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):4961-6. doi: 10.1073/pnas.0610814104. Epub 2007 Mar 12. Proc Natl Acad Sci U S A. 2007. PMID: 17360365 Free PMC article.
Androgens and spermatogenesis: lessons from transgenic mouse models.
Verhoeven G, Willems A, Denolet E, Swinnen JV, De Gendt K. Verhoeven G, et al. Philos Trans R Soc Lond B Biol Sci. 2010 May 27;365(1546):1537-56. doi: 10.1098/rstb.2009.0117. Philos Trans R Soc Lond B Biol Sci. 2010. PMID: 20403868 Free PMC article. Review.
310 results