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Addition of histamine to interleukin 2 treatment augments type 1 T-cell responses in patients with melanoma in vivo: immunologic results from a randomized clinical trial of interleukin 2 with or without histamine (MP 104).
Asemissen AM, Scheibenbogen C, Letsch A, Hellstrand K, Thorén F, Gehlsen K, Schmittel A, Thiel E, Keilholz U. Asemissen AM, et al. Among authors: hellstrand k. Clin Cancer Res. 2005 Jan 1;11(1):290-7. Clin Cancer Res. 2005. PMID: 15671558 Clinical Trial.
Results from a randomized phase III study comparing combined treatment with histamine dihydrochloride plus interleukin-2 versus interleukin-2 alone in patients with metastatic melanoma.
Agarwala SS, Glaspy J, O'Day SJ, Mitchell M, Gutheil J, Whitman E, Gonzalez R, Hersh E, Feun L, Belt R, Meyskens F, Hellstrand K, Wood D, Kirkwood JM, Gehlsen KR, Naredi P. Agarwala SS, et al. Among authors: hellstrand k. J Clin Oncol. 2002 Jan 1;20(1):125-33. doi: 10.1200/JCO.2002.20.1.125. J Clin Oncol. 2002. PMID: 11773161 Clinical Trial.
Histamine: a novel approach to cancer immunotherapy.
Hellstrand K, Brune M, Naredi P, Mellqvist UH, Hansson M, Gehlsen KR, Hermodsson S. Hellstrand K, et al. Cancer Invest. 2000;18(4):347-55. doi: 10.3109/07357900009012178. Cancer Invest. 2000. PMID: 10808371 Review.
Results of a multicenter randomized study to evaluate the safety and efficacy of combined immunotherapy with interleukin-2, interferon-{alpha}2b and histamine dihydrochloride versus dacarbazine in patients with stage IV melanoma.
Middleton M, Hauschild A, Thomson D, Anderson R, Burdette-Radoux S, Gehlsen K, Hellstrand K, Naredi P. Middleton M, et al. Among authors: hellstrand k. Ann Oncol. 2007 Oct;18(10):1691-7. doi: 10.1093/annonc/mdm331. Epub 2007 Aug 20. Ann Oncol. 2007. PMID: 17709802 Free article. Clinical Trial.
198 results