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Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists.
Palin R, Barn DR, Clark JK, Cottney JE, Cowley PM, Crockatt M, Evans L, Feilden H, Goodwin RR, Griekspoor F, Grove SJ, Houghton AK, Jones PS, Morphy RJ, Smith AR, Sundaram H, Vrolijk D, Weston MA, Wishart G, Wren P. Palin R, et al. Among authors: weston ma. Bioorg Med Chem Lett. 2005 Feb 1;15(3):589-93. doi: 10.1016/j.bmcl.2004.11.049. Bioorg Med Chem Lett. 2005. PMID: 15664818
Rapid access towards follow-up NOP receptor agonists using a knowledge based approach.
Palin R, Clark JK, Evans L, Feilden H, Fletcher D, Hamilton NM, Houghton AK, Jones PS, McArthur D, Montgomery B, Ratcliffe PD, Smith AR, Sutherland A, Weston MA, Wishart G. Palin R, et al. Among authors: weston ma. Bioorg Med Chem Lett. 2009 Nov 15;19(22):6441-6. doi: 10.1016/j.bmcl.2009.09.028. Epub 2009 Sep 12. Bioorg Med Chem Lett. 2009. PMID: 19818611
Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist.
Brown AR, Bosies M, Cameron H, Clark J, Cowley A, Craighead M, Elmore MA, Firth A, Goodwin R, Goutcher S, Grant E, Grassie M, Grove SJ, Hamilton NM, Hampson H, Hillier A, Ho KK, Kiczun M, Kingsbury C, Kultgen SG, Littlewood PT, Lusher SJ, Macdonald S, McIntosh L, McIntyre T, Mistry A, Morphy JR, Nimz O, Ohlmeyer M, Pick J, Rankovic Z, Sherborne B, Smith A, Speake M, Spinks G, Thomson F, Watson L, Weston M. Brown AR, et al. Among authors: weston m. Bioorg Med Chem Lett. 2011 Jan 1;21(1):137-40. doi: 10.1016/j.bmcl.2010.11.054. Epub 2010 Nov 16. Bioorg Med Chem Lett. 2011. PMID: 21129964
Bird tolerance to humans in open tropical ecosystems.
Mikula P, Tomášek O, Romportl D, Aikins TK, Avendaño JE, Braimoh-Azaki BDA, Chaskda A, Cresswell W, Cunningham SJ, Dale S, Favoretto GR, Floyd KS, Glover H, Grim T, Henry DAW, Holmern T, Hromada M, Iwajomo SB, Lilleyman A, Magige FJ, Martin RO, de A Maximiano MF, Nana ED, Ncube E, Ndaimani H, Nelson E, van Niekerk JH, Pienaar C, Piratelli AJ, Pistorius P, Radkovic A, Reynolds C, Røskaft E, Shanungu GK, Siqueira PR, Tarakini T, Tejeiro-Mahecha N, Thompson ML, Wamiti W, Wilson M, Tye DRC, Tye ND, Vehtari A, Tryjanowski P, Weston MA, Blumstein DT, Albrecht T. Mikula P, et al. Among authors: weston ma. Nat Commun. 2023 Apr 20;14(1):2146. doi: 10.1038/s41467-023-37936-5. Nat Commun. 2023. PMID: 37081049 Free PMC article.
55 results