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687 results

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The Apc 1322T mouse develops severe polyposis associated with submaximal nuclear beta-catenin expression.
Pollard P, Deheragoda M, Segditsas S, Lewis A, Rowan A, Howarth K, Willis L, Nye E, McCart A, Mandir N, Silver A, Goodlad R, Stamp G, Cockman M, East P, Spencer-Dene B, Poulsom R, Wright N, Tomlinson I. Pollard P, et al. Among authors: silver a. Gastroenterology. 2009 Jun;136(7):2204-2213.e1-13. doi: 10.1053/j.gastro.2009.02.058. Epub 2009 Feb 25. Gastroenterology. 2009. PMID: 19248780
Evidence for an association between compound heterozygosity for germ line mutations in the hemochromatosis (HFE) gene and increased risk of colorectal cancer.
Robinson JP, Johnson VL, Rogers PA, Houlston RS, Maher ER, Bishop DT, Evans DG, Thomas HJ, Tomlinson IP, Silver AR. Robinson JP, et al. Among authors: silver ar. Cancer Epidemiol Biomarkers Prev. 2005 Jun;14(6):1460-3. doi: 10.1158/1055-9965.EPI-04-0672. Cancer Epidemiol Biomarkers Prev. 2005. PMID: 15941956
Genetic basis of variation in adenoma multiplicity in ApcMin/+ Mom1S mice.
Haines J, Johnson V, Pack K, Suraweera N, Slijepcevic P, Cabuy E, Coster M, Ilyas M, Wilding J, Sieber O, Bodmer W, Tomlinson I, Silver A. Haines J, et al. Among authors: silver a. Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):2868-73. doi: 10.1073/pnas.0500039102. Epub 2005 Feb 14. Proc Natl Acad Sci U S A. 2005. PMID: 15710876 Free PMC article.
Refining molecular analysis in the pathways of colorectal carcinogenesis.
Rowan A, Halford S, Gaasenbeek M, Kemp Z, Sieber O, Volikos E, Douglas E, Fiegler H, Carter N, Talbot I, Silver A, Tomlinson I. Rowan A, et al. Among authors: silver a. Clin Gastroenterol Hepatol. 2005 Nov;3(11):1115-23. doi: 10.1016/s1542-3565(05)00618-x. Clin Gastroenterol Hepatol. 2005. PMID: 16271343
Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice.
Segditsas S, Sieber O, Deheragoda M, East P, Rowan A, Jeffery R, Nye E, Clark S, Spencer-Dene B, Stamp G, Poulsom R, Suraweera N, Silver A, Ilyas M, Tomlinson I. Segditsas S, et al. Among authors: silver a. Hum Mol Genet. 2008 Dec 15;17(24):3864-75. doi: 10.1093/hmg/ddn286. Epub 2008 Sep 9. Hum Mol Genet. 2008. PMID: 18782851 Free PMC article.
Disease severity and genetic pathways in attenuated familial adenomatous polyposis vary greatly but depend on the site of the germline mutation.
Sieber OM, Segditsas S, Knudsen AL, Zhang J, Luz J, Rowan AJ, Spain SL, Thirlwell C, Howarth KM, Jaeger EE, Robinson J, Volikos E, Silver A, Kelly G, Aretz S, Frayling I, Hutter P, Dunlop M, Guenther T, Neale K, Phillips R, Heinimann K, Tomlinson IP. Sieber OM, et al. Among authors: silver a. Gut. 2006 Oct;55(10):1440-8. doi: 10.1136/gut.2005.087106. Epub 2006 Feb 4. Gut. 2006. PMID: 16461775 Free PMC article.
687 results