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Page 1
A practical synthesis of gramicidin s and sugar amino Acid containing analogues.
Grotenbreg GM, Kronemeijer M, Timmer MS, El Oualid F, van Well RM, Verdoes M, Spalburg E, van Hooft PA, de Neeling AJ, Noort D, van Boom JH, van der Marel GA, Overkleeft HS, Overhand M. Grotenbreg GM, et al. Among authors: noort d. J Org Chem. 2004 Nov 12;69(23):7851-9. doi: 10.1021/jo0487449. J Org Chem. 2004. PMID: 15527261
Structural and biological evaluation of some loloatin C analogues.
Tuin AW, Grotenbreg GM, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, van der Marel GA, Noort D, Overkleeft HS, Overhand M. Tuin AW, et al. Among authors: noort d. Bioorg Med Chem. 2009 Sep 1;17(17):6233-40. doi: 10.1016/j.bmc.2009.07.049. Epub 2009 Jul 25. Bioorg Med Chem. 2009. PMID: 19679485
An adamantyl amino acid containing gramicidin S analogue with broad spectrum antibacterial activity and reduced hemolytic activity.
Kapoerchan VV, Knijnenburg AD, Niamat M, Spalburg E, de Neeling AJ, Nibbering PH, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Kapoerchan VV, et al. Among authors: noort d. Chemistry. 2010 Oct 25;16(40):12174-81. doi: 10.1002/chem.201001686. Chemistry. 2010. PMID: 20848624
Exploring the conformational and biological versatility of β-turn-modified gramicidin S by using sugar amino acid homologues that vary in ring size.
Knijnenburg AD, Tuin AW, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Knijnenburg AD, et al. Among authors: noort d. Chemistry. 2011 Mar 28;17(14):3995-4004. doi: 10.1002/chem.201002895. Epub 2011 Mar 1. Chemistry. 2011. PMID: 21365698
Synthesis and evaluation of strand and turn modified ring-extended gramicidin S derivatives.
Knijnenburg AD, Kapoerchan VV, Grotenbreg GM, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, Ravensbergen B, Nibbering PH, van der Marel GA, Overkleeft HS, Overhand M. Knijnenburg AD, et al. Among authors: noort d. Bioorg Med Chem. 2011 Jun 1;19(11):3402-9. doi: 10.1016/j.bmc.2011.04.031. Epub 2011 Apr 22. Bioorg Med Chem. 2011. PMID: 21561781
'Inverted' analogs of the antibiotic gramicidin S with an improved biological profile.
Kapoerchan VV, Knijnenburg AD, Keizer P, Spalburg E, de Neeling AJ, Mars-Groenendijk RH, Noort D, Otero JM, Llamas-Saiz AL, van Raaij MJ, van der Marel GA, Overkleeft HS, Overhand M. Kapoerchan VV, et al. Among authors: noort d. Bioorg Med Chem. 2012 Oct 15;20(20):6059-62. doi: 10.1016/j.bmc.2012.08.038. Epub 2012 Aug 31. Bioorg Med Chem. 2012. PMID: 22989907
119 results