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Intrinsic defect in T cell production of interleukin (IL)-13 in the absence of both IL-5 and eotaxin precludes the development of eosinophilia and airways hyperreactivity in experimental asthma.
Mattes J, Yang M, Mahalingam S, Kuehr J, Webb DC, Simson L, Hogan SP, Koskinen A, McKenzie AN, Dent LA, Rothenberg ME, Matthaei KI, Young IG, Foster PS. Mattes J, et al. Among authors: mahalingam s. J Exp Med. 2002 Jun 3;195(11):1433-44. doi: 10.1084/jem.20020009. J Exp Med. 2002. PMID: 12045241 Free PMC article.
Interleukin-5 and eosinophils as therapeutic targets for asthma.
Foster PS, Hogan SP, Yang M, Mattes J, Young IG, Matthaei KI, Kumar RK, Mahalingam S, Webb DC. Foster PS, et al. Among authors: mahalingam s. Trends Mol Med. 2002 Apr;8(4):162-7. doi: 10.1016/s1471-4914(02)02302-x. Trends Mol Med. 2002. PMID: 11927273
Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway.
Wong GW, Foster PS, Yasuda S, Qi JC, Mahalingam S, Mellor EA, Katsoulotos G, Li L, Boyce JA, Krilis SA, Stevens RL. Wong GW, et al. Among authors: mahalingam s. J Biol Chem. 2002 Nov 1;277(44):41906-15. doi: 10.1074/jbc.M205868200. Epub 2002 Aug 22. J Biol Chem. 2002. PMID: 12194977 Free article.
Chemokines and viruses: friends or foes?
Mahalingam S, Friedland JS, Heise MT, Rulli NE, Meanger J, Lidbury BA. Mahalingam S, et al. Trends Microbiol. 2003 Aug;11(8):383-91. doi: 10.1016/s0966-842x(03)00157-4. Trends Microbiol. 2003. PMID: 12915096 Review. No abstract available.
451 results