Van Antwerpen P - Search Results

1

In vitro comparative assessment of the scavenging activity against three reactive oxygen species of non-steroidal anti-inflammatory drugs from the oxicam and sulfoanilide families.

Van Antwerpen P, Nève J. Van Antwerpen P, et al. Eur J Pharmacol. 2004 Aug 2;496(1-3):55-61. doi: 10.1016/j.ejphar.2004.06.017. Eur J Pharmacol. 2004. PMID: 15288575

2

Thiol-containing molecules interact with the myeloperoxidase/H2O2/chloride system to inhibit LDL oxidation.

Van Antwerpen P, Boudjeltia KZ, Babar S, Legssyer I, Moreau P, Moguilevsky N, Vanhaeverbeek M, Ducobu J, Nève J. Van Antwerpen P, et al. Biochem Biophys Res Commun. 2005 Nov 11;337(1):82-8. doi: 10.1016/j.bbrc.2005.09.013. Biochem Biophys Res Commun. 2005. PMID: 16171780

3

Captopril inhibits the oxidative modification of apolipoprotein B-100 caused by myeloperoxydase in a comparative in vitro assay of angiotensin converting enzyme inhibitors.

Van Antwerpen P, Legssyer I, Zouaoui Boudjeltia K, Babar S, Moreau P, Moguilevsky N, Vanhaeverbeek M, Ducobu J, Nève J. Van Antwerpen P, et al. Eur J Pharmacol. 2006 May 10;537(1-3):31-6. doi: 10.1016/j.ejphar.2006.03.022. Epub 2006 Mar 20. Eur J Pharmacol. 2006. PMID: 16631159

4

Inhibition of the myeloperoxidase chlorinating activity by non-steroidal anti-inflammatory drugs: flufenamic acid and its 5-chloro-derivative directly interact with a recombinant human myeloperoxidase to inhibit the synthesis of hypochlorous acid.

Van Antwerpen P, Dufrasne F, Lequeux M, Boudjeltia KZ, Lessgyer I, Babar S, Moreau P, Moguilevsky N, Vanhaeverbeek M, Ducobu J, Nève J. Van Antwerpen P, et al. Eur J Pharmacol. 2007 Sep 10;570(1-3):235-43. doi: 10.1016/j.ejphar.2007.05.057. Epub 2007 Jun 12. Eur J Pharmacol. 2007. PMID: 17610876

5

Probucol does not inhibit myeloperoxidase-dependent low-density lipoprotein oxidation as a potent protective effect in atherosclerosis.

Van Antwerpen P, Néve J, Moreau P, Boudjeltia KZ, Vanhaeverbeek M, Prévost M, Babar S, Legssyer I, Moguilevsky N, Ducobu J. Van Antwerpen P, et al. J Cardiovasc Pharmacol. 2007 Sep;50(3):350-1. doi: 10.1097/FJC.0b013e31809501dc. J Cardiovasc Pharmacol. 2007. PMID: 17878766 No abstract available.

6

Conception of myeloperoxidase inhibitors derived from flufenamic acid by computational docking and structure modification.

Van Antwerpen P, Prévost M, Zouaoui-Boudjeltia K, Babar S, Legssyer I, Moreau P, Moguilevsky N, Vanhaeverbeek M, Ducobu J, Nève J, Dufrasne F. Van Antwerpen P, et al. Bioorg Med Chem. 2008 Feb 15;16(4):1702-20. doi: 10.1016/j.bmc.2007.11.025. Epub 2007 Nov 13. Bioorg Med Chem. 2008. PMID: 18063373

7

Development and validation of a screening procedure for the assessment of inhibition using a recombinant enzyme.

Van Antwerpen P, Moreau P, Zouaoui Boudjeltia K, Babar S, Dufrasne F, Moguilevsky N, Vanhaeverbeek M, Ducobu J, Nève J. Van Antwerpen P, et al. Talanta. 2008 Apr 15;75(2):503-10. doi: 10.1016/j.talanta.2007.11.040. Epub 2007 Nov 22. Talanta. 2008. PMID: 18371913

8

A large-bolus injection, but not continuous infusion of sodium selenite improves outcome in peritonitis.

Wang Z, Forceville X, Van Antwerpen P, Piagnerelli M, Ahishakiye D, Macours P, De Backer D, Neve J, Vincent JL. Wang Z, et al. Among authors: van antwerpen p. Shock. 2009 Aug;32(2):140-6. doi: 10.1097/SHK.0b013e318193c35d. Shock. 2009. PMID: 19602943

9

Glycosylation pattern of mature dimeric leukocyte and recombinant monomeric myeloperoxidase: glycosylation is required for optimal enzymatic activity.

Van Antwerpen P, Slomianny MC, Boudjeltia KZ, Delporte C, Faid V, Calay D, Rousseau A, Moguilevsky N, Raes M, Vanhamme L, Furtmüller PG, Obinger C, Vanhaeverbeek M, Nève J, Michalski JC. Van Antwerpen P, et al. J Biol Chem. 2010 May 21;285(21):16351-9. doi: 10.1074/jbc.M109.089748. Epub 2010 Mar 23. J Biol Chem. 2010. PMID: 20332087 Free PMC article.

10

Structure-based design, synthesis, and pharmacological evaluation of 3-(aminoalkyl)-5-fluoroindoles as myeloperoxidase inhibitors.

Soubhye J, Prévost M, Van Antwerpen P, Zouaoui Boudjeltia K, Rousseau A, Furtmüller PG, Obinger C, Vanhaeverbeek M, Ducobu J, Néve J, Gelbcke M, Dufrasne FO. Soubhye J, et al. Among authors: van antwerpen p. J Med Chem. 2010 Dec 23;53(24):8747-59. doi: 10.1021/jm1009988. Epub 2010 Nov 22. J Med Chem. 2010. PMID: 21090682

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