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A mouse model of the schizophrenia-associated 1q21.1 microdeletion syndrome exhibits altered mesolimbic dopamine transmission.
Nielsen J, Fejgin K, Sotty F, Nielsen V, Mørk A, Christoffersen CT, Yavich L, Lauridsen JB, Clausen D, Larsen PH, Egebjerg J, Werge TM, Kallunki P, Christensen KV, Didriksen M. Nielsen J, et al. Among authors: mork a. Transl Psychiatry. 2017 Nov 30;7(11):1261. doi: 10.1038/s41398-017-0011-8. Transl Psychiatry. 2017. PMID: 29187755 Free PMC article.
Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder.
Mørk A, Pehrson A, Brennum LT, Nielsen SM, Zhong H, Lassen AB, Miller S, Westrich L, Boyle NJ, Sánchez C, Fischer CW, Liebenberg N, Wegener G, Bundgaard C, Hogg S, Bang-Andersen B, Stensbøl TB. Mørk A, et al. J Pharmacol Exp Ther. 2012 Mar;340(3):666-75. doi: 10.1124/jpet.111.189068. Epub 2011 Dec 9. J Pharmacol Exp Ther. 2012. PMID: 22171087
Combination of escitalopram and a 5-HT(₁A) receptor antagonist selectively decreases the extracellular levels of dopamine in the nucleus accumbens relative to striatum through 5-HT(₂C) receptor stimulation; suggestive of antipsychotic potential.
Hovelsø N, Sager TN, Mørk A. Hovelsø N, et al. Among authors: mork a. Pharmacol Biochem Behav. 2011 Jan;97(3):479-85. doi: 10.1016/j.pbb.2010.10.003. Epub 2010 Oct 16. Pharmacol Biochem Behav. 2011. PMID: 20937301
162 results