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Her-2/neu and EGFR tyrosine kinase activation predict the efficacy of trastuzumab-based therapy in patients with metastatic breast cancer.
Hudelist G, Köstler WJ, Czerwenka K, Kubista E, Attems J, Müller R, Gschwantler-Kaulich D, Manavi M, Huber I, Hoschützky H, Zielinski CC, Singer CF. Hudelist G, et al. Among authors: kostler wj. Int J Cancer. 2006 Mar 1;118(5):1126-34. doi: 10.1002/ijc.21492. Int J Cancer. 2006. PMID: 16161043 Free article. Clinical Trial.
High-level ERBB2 gene amplification is associated with a particularly short time-to-metastasis, but results in a high rate of complete response once trastuzumab-based therapy is offered in the metastatic setting.
Fuchs EM, Köstler WJ, Horvat R, Hudelist G, Kubista E, Attems J, Zielinski CC, Singer CF. Fuchs EM, et al. Among authors: kostler wj. Int J Cancer. 2014 Jul 1;135(1):224-31. doi: 10.1002/ijc.28660. Epub 2014 Jan 28. Int J Cancer. 2014. PMID: 24311197 Free article.
125 results