Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

15 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
The development of potent non-peptidic PTP-1B inhibitors.
Dufresne C, Roy P, Wang Z, Asante-Appiah E, Cromlish W, Boie Y, Forghani F, Desmarais S, Wang Q, Skorey K, Waddleton D, Ramachandran C, Kennedy BP, Xu L, Gordon R, Chan CC, Leblanc Y. Dufresne C, et al. Among authors: waddleton d. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1039-42. doi: 10.1016/j.bmcl.2003.11.048. Bioorg Med Chem Lett. 2004. PMID: 15013019
Structure based design of a series of potent and selective non peptidic PTP-1B inhibitors.
Lau CK, Bayly CI, Gauthier JY, Li CS, Therien M, Asante-Appiah E, Cromlish W, Boie Y, Forghani F, Desmarais S, Wang Q, Skorey K, Waddleton D, Payette P, Ramachandran C, Kennedy BP, Scapin G. Lau CK, et al. Among authors: waddleton d. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1043-8. doi: 10.1016/j.bmcl.2003.11.076. Bioorg Med Chem Lett. 2004. PMID: 15013020
Synthesis of a novel peptidic photoaffinity probe for the PTP-1B enzyme.
Thérien M, Skorey K, Zamboni R, Li CS, Lau CK, LeRiche T, Linh Truong V, Waddleton D, Ramachandran C. Thérien M, et al. Among authors: waddleton d. Bioorg Med Chem Lett. 2004 May 3;14(9):2319-22. doi: 10.1016/j.bmcl.2004.01.101. Bioorg Med Chem Lett. 2004. PMID: 15081032
Development of a liver-targeted stearoyl-CoA desaturase (SCD) inhibitor (MK-8245) to establish a therapeutic window for the treatment of diabetes and dyslipidemia.
Oballa RM, Belair L, Black WC, Bleasby K, Chan CC, Desroches C, Du X, Gordon R, Guay J, Guiral S, Hafey MJ, Hamelin E, Huang Z, Kennedy B, Lachance N, Landry F, Li CS, Mancini J, Normandin D, Pocai A, Powell DA, Ramtohul YK, Skorey K, Sørensen D, Sturkenboom W, Styhler A, Waddleton DM, Wang H, Wong S, Xu L, Zhang L. Oballa RM, et al. Among authors: waddleton dm. J Med Chem. 2011 Jul 28;54(14):5082-96. doi: 10.1021/jm200319u. Epub 2011 Jun 28. J Med Chem. 2011. PMID: 21661758
The structural basis for the selectivity of benzotriazole inhibitors of PTP1B.
Scapin G, Patel SB, Becker JW, Wang Q, Desponts C, Waddleton D, Skorey K, Cromlish W, Bayly C, Therien M, Gauthier JY, Li CS, Lau CK, Ramachandran C, Kennedy BP, Asante-Appiah E. Scapin G, et al. Among authors: waddleton d. Biochemistry. 2003 Oct 7;42(39):11451-9. doi: 10.1021/bi035098j. Biochemistry. 2003. PMID: 14516196
15 results